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Details

Stereochemistry ACHIRAL
Molecular Formula C9H6O2
Molecular Weight 146.1427
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHROMONE

SMILES

O=C1C=COC2=C1C=CC=C2

InChI

InChIKey=OTAFHZMPRISVEM-UHFFFAOYSA-N
InChI=1S/C9H6O2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H

HIDE SMILES / InChI

Molecular Formula C9H6O2
Molecular Weight 146.1427
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors.
2009-01-15
Efficient synthesis of chromone and flavonoid derivatives with diverse heterocyclic units.
2008-12-01
pH controlled release of chromone from chromone-Fe3O4 nanoparticles.
2008-11-05
Chemical substructures that enrich for biological activity.
2008-11-01
Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648).
2008-08-28
Relationship between structure and antioxidative properties of some 3-formylchromone derivatives.
2008-07
Synthesis, spectroscopy and alkylating properties of Pd(II) complexes of phosphorohydrazones of coumarin and chromone with potential antibacterial activity.
2008-06-11
[Study of the Saposhnikovia divaricata with space mutagenesis by Fourier transform infrared spectroscopy].
2008-06
3D-QSAR studies on chromone derivatives as HIV-1 protease inhibitors: application of molecular field analysis.
2008-06
Rhodium-catalyzed oxidative coupling between salicylaldehydes and internal alkynes with C-H bond cleavage to produce 2,3-disubstituted chromones.
2008-05-05
Modeling and synthesis of novel tight-binding inhibitors of cytochrome P450 2C9.
2008-04-01
BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis.
2008-04
4'-methoxy-2-styrylchromone a novel microtubule-stabilizing antimitotic agent.
2008-02-15
Chromone and chromanone derivatives as strand transfer inhibitors of HIV-1 integrase.
2008-01
Influence of phosphorohydrazone derivatives of benzopyrones on polymerization and viscosity of fibrin.
2008
Effect of beta-cyclodextrin nanocavity confinement on the photophysics of robinetin.
2007-12-14
Biological activity of 3-formylchromones and related compounds.
2007-11-21
Spectra and DNA-binding affinities of Copper(II), Nickel(II) complexes with a novel glycine Schiff base derived from chromone.
2007-11
Synthesis and biological evaluation of the mitochondrial complex 1 inhibitor 2-[4-(4-fluorobutyl)benzylsulfanyl]-3-methylchromene-4-one as a potential cardiac positron emission tomography tracer.
2007-09-06
(1)H and (13)C NMR signal assignments of paecilin A and B, two new chromone derivatives from mangrove endophytic fungus Paecilomyces sp. (tree 1-7).
2007-09
Anti-cancer and immunostimulatory activity of chromones and other constituents from Cassia petersiana.
2007-08-22
Design, syntheses, and antitumor activity of novel chromone and aurone derivatives.
2007-08-01
The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation.
2007-07-13
Structure of the cytochrome b6f complex: quinone analogue inhibitors as ligands of heme cn.
2007-06-29
Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp.
2007-05-01
A comparison of stigmatellin conformations, free and bound to the photosynthetic reaction center and the cytochrome bc1 complex.
2007-04-20
A chromone analog inhibits TNF-alpha induced expression of cell adhesion molecules on human endothelial cells via blocking NF-kappaB activation.
2007-04-15
Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2.
2007-04-15
Synthesis and insecticidal activity of chromanone and chromone analogues of diacylhydrazines.
2007-03-01
Fingerprint analysis of the fruits of Cnidium monnieri extract by high-performance liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry.
2007-02-19
A new chromone from Cassia nodosa.
2006-12-01
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
2006-12-01
In vivo antitumor, in vitro antibacterial activity and alkylating properties of phosphorohydrazine derivatives of coumarin and chromone.
2006-11
Synthesis of 2,3,6,8-tetrasubstituted chromone scaffolds.
2006-09-01
[The synthesis of arginine derivatives of chromone and azauracil].
2006-07-01
Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells.
2006-06-29
Chromone derivatives from the filamentous fungus Lachnum sp. BCC 2424.
2006-06
Phototransformation of the herbicide sulcotrione on maize cuticular wax.
2006-05-01
Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors.
2006
Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach.
2005-12-01
Sesquiterpene chromones from Ferula fukanensis and their nitric oxide production inhibitory effects.
2005-12
Inhibition of epidermal growth factor-induced cell transformation by tannins.
2005-09
Synthesis and in vivo analgesic and anti-inflammatory activity of some bi heterocyclic coumarin derivatives.
2005-09
Reactions of 3-formylchromone with active methylene and methyl compounds and some subsequent reactions of the resulting condensation products.
2005-08-31
Time dependent density functional theory study of electronic absorption properties of lead(II) complexes with a series of hydroxyflavones.
2005-08-04
Rotenoids and isoflavones from Sarcolobus globosus.
2005-08
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.
2005-06-15
Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors.
2005-06-02
(2Z)-3-(5-Hydroxy-4-oxo-4H-chromen-3-yl)acrylonitrile.
2005-04
[Preparative isolation and purification of cinnamoyl-C-glycoside chromone from aloe vera by high-speed countercurrent chromatography].
2005-01
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:59:25 GMT 2025
Edited
by admin
on Mon Mar 31 19:59:25 GMT 2025
Record UNII
20C556MJ76
Record Status Validated (UNII)
Record Version
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Name Type Language
1,4-BENZOPYRONE
Preferred Name English
CHROMONE
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
207-737-9
Created by admin on Mon Mar 31 19:59:25 GMT 2025 , Edited by admin on Mon Mar 31 19:59:25 GMT 2025
PRIMARY
FDA UNII
20C556MJ76
Created by admin on Mon Mar 31 19:59:25 GMT 2025 , Edited by admin on Mon Mar 31 19:59:25 GMT 2025
PRIMARY
PUBCHEM
10286
Created by admin on Mon Mar 31 19:59:25 GMT 2025 , Edited by admin on Mon Mar 31 19:59:25 GMT 2025
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EPA CompTox
DTXSID40197680
Created by admin on Mon Mar 31 19:59:25 GMT 2025 , Edited by admin on Mon Mar 31 19:59:25 GMT 2025
PRIMARY
WIKIPEDIA
CHROMONE
Created by admin on Mon Mar 31 19:59:25 GMT 2025 , Edited by admin on Mon Mar 31 19:59:25 GMT 2025
PRIMARY
CAS
491-38-3
Created by admin on Mon Mar 31 19:59:25 GMT 2025 , Edited by admin on Mon Mar 31 19:59:25 GMT 2025
PRIMARY
CHEBI
72013
Created by admin on Mon Mar 31 19:59:25 GMT 2025 , Edited by admin on Mon Mar 31 19:59:25 GMT 2025
PRIMARY