Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H11N3 |
| Molecular Weight | 197.2358 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC2=C(NC3=C2C=CC=C3)N=C1N
InChI
InChIKey=IVLCGFRPPGNALI-UHFFFAOYSA-N
InChI=1S/C12H11N3/c1-7-6-9-8-4-2-3-5-10(8)14-12(9)15-11(7)13/h2-6H,1H3,(H3,13,14,15)
| Molecular Formula | C12H11N3 |
| Molecular Weight | 197.2358 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Carcinogenicity in mice and rats of heterocyclic amines in cooked foods. | 1986 Aug |
|
| Initiating activity in a two-stage mouse skin model of nine mutagenic pyrolysates of amino acids, soybean globulin and proteinaceous food. | 1987 Sep |
|
| Inhibition of human brain aromatic L-amino acid decarboxylase by cooked food-derived 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) and other heterocyclic amines. | 1990 Aug 24 |
|
| In vitro metabolism of two heterocyclic amines, 2-amino-9H-pyrido[2,3-b]indole (A(alpha)C) and 2-amino-3-methyl-9H-pyridol2,3-b]indole (MeA(alpha)C) in human and rat hepatic microsomes. | 2002 Mar |
|
| Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC) and 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and identification of DNA adducts in organs from rats dosed with MeAalphaC. | 2004 Aug |
|
| Modulation of cytochrome P450 1A1 by food-derived heterocyclic aromatic amines. | 2004 Jul 1 |
|
| Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAalphaC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes. | 2004 May |
|
| Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. | 2008 Jun |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:13:59 GMT 2023
by
admin
on
Fri Dec 15 19:13:59 GMT 2023
|
| Record UNII |
20AI638WCJ
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
20AI638WCJ
Created by
admin on Fri Dec 15 19:13:59 GMT 2023 , Edited by admin on Fri Dec 15 19:13:59 GMT 2023
|
PRIMARY | |||
|
68006-83-7
Created by
admin on Fri Dec 15 19:13:59 GMT 2023 , Edited by admin on Fri Dec 15 19:13:59 GMT 2023
|
PRIMARY | |||
|
C017821
Created by
admin on Fri Dec 15 19:13:59 GMT 2023 , Edited by admin on Fri Dec 15 19:13:59 GMT 2023
|
PRIMARY | |||
|
DTXSID5043766
Created by
admin on Fri Dec 15 19:13:59 GMT 2023 , Edited by admin on Fri Dec 15 19:13:59 GMT 2023
|
PRIMARY | |||
|
62244
Created by
admin on Fri Dec 15 19:13:59 GMT 2023 , Edited by admin on Fri Dec 15 19:13:59 GMT 2023
|
PRIMARY |