Botensilimab

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 04:07:44 GMT 2025` Edited by `admin` on `Wed Apr 02 04:07:44 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	1Z5YC3ME5N
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

botensilimab [INN]

Preferred Name

English

Botensilimab

Official Name

English

Botensilimab [WHO-DD]

Common Name

English

Immunoglobulin G1 [240-aspartic acid,331-leucine,333-glutamic acid,de-C-terminal-lysine], anti-(human cytotoxic T-lymphocyte-associated protein 4) (human monoclonal AGEN1181 ?1-chain), disulfide with human monoclonal AGEN1181 ?-chain, dimer

Common Name

English

AGEN1181

Code

English

AGEN-1181

Code

English

Immunoglobulin G1-kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CD152)], Homo sapiens monoclonal antibody; gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV3-21*01 (99.0%) -(IGHD) - IGHJ3*02 (92.9%) M123>L (11

Common Name

English

BOTENSILIMAB [USAN]

Common Name

English

Code System Code Type Description

FDA UNII

1Z5YC3ME5N

Created by admin on Wed Apr 02 04:07:44 GMT 2025 , Edited by admin on Wed Apr 02 04:07:44 GMT 2025

PRIMARY

INN

11659

Created by admin on Wed Apr 02 04:07:44 GMT 2025 , Edited by admin on Wed Apr 02 04:07:44 GMT 2025

PRIMARY

INN

CAS

2408310-37-0

Created by admin on Wed Apr 02 04:07:44 GMT 2025 , Edited by admin on Wed Apr 02 04:07:44 GMT 2025

PRIMARY

USAN

KL-157

Created by admin on Wed Apr 02 04:07:44 GMT 2025 , Edited by admin on Wed Apr 02 04:07:44 GMT 2025

PRIMARY

NCI_THESAURUS

C158557

Created by admin on Wed Apr 02 04:07:44 GMT 2025 , Edited by admin on Wed Apr 02 04:07:44 GMT 2025

PRIMARY

SMS_ID

300000032314

Created by admin on Wed Apr 02 04:07:44 GMT 2025 , Edited by admin on Wed Apr 02 04:07:44 GMT 2025

PRIMARY

From	To
1_221	3_214
2_221	4_214
1_227	2_227
1_230	2_230
1_22	1_96
2_22	2_96
1_145	1_201
2_145	2_201
1_262	1_322
2_262	2_322
1_368	1_426
2_368	2_426
3_23	3_88
4_23	4_88
3_134	3_194
4_134	4_194

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					KYU4T5WAI2

CYTOTOXIC T-LYMPHOCYTE PROTEIN 4

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					1Z5YC3ME5N

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL