AZD-2423

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H29ClFN5O2
Molecular Weight	425.928
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)N1CCN[C@H](C1)C(=O)N2CCN(CC2)C(=O)NC3=CC(F)=C(Cl)C=C3

InChI

InChIKey=SRWQVWAIVQXPJY-QGZVFWFLSA-N

InChI=1S/C20H29ClFN5O2/c1-20(2,3)27-7-6-23-17(13-27)18(28)25-8-10-26(11-9-25)19(29)24-14-4-5-15(21)16(22)12-14/h4-5,12,17,23H,6-11,13H2,1-3H3,(H,24,29)/t17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C20H29ClFN5O2
Molecular Weight	425.928
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

C_max

Value	Dose	Co-administered	Analyte	Population
198 nM CLINICAL TRIAL clinicaltrials.gov/ct2/show/results/NCT01215279	100 mg 1 times / day steady-state, oral dose: 100 mg route of administration: Oral experiment type: STEADY-STATE co-administered:		AZD-2423 plasma	Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN

AUC

Value	Dose	Co-administered	Analyte	Population
2780 nM × h CLINICAL TRIAL clinicaltrials.gov/ct2/show/results/NCT01215279	100 mg 1 times / day steady-state, oral dose: 100 mg route of administration: Oral experiment type: STEADY-STATE co-administered:		AZD-2423 plasma	Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:58:32 GMT 2025` Edited by `admin` on `Mon Mar 31 19:58:32 GMT 2025`
Record UNII	1W47471992
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AZD 2423 [WHO-DD]

Preferred Name

English

AZD-2423

Common Name

English

4-((2R)-4-TERT-BUTYLPIPERAZINE-2-CARBONYL)-N-(4-CHLORO-3-FLUOROPHENYL)PIPERAZINE-1-CARBOXAMIDE

Systematic Name

English

Code System Code Type Description

FDA UNII

1W47471992