Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C16H8N2O6S4.2Na |
| Molecular Weight | 498.484 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 3 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Na+].[O-]S(=O)(=O)C1=C(C=CC(=C1)N=C=S)\C=C\C2=C(C=C(C=C2)N=C=S)S([O-])(=O)=O
InChI
InChIKey=GEPAYBXVXXBSKP-SEPHDYHBSA-L
InChI=1S/C16H10N2O6S4.2Na/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24;;/h1-8H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2/b2-1+;;
| Molecular Formula | C16H8N2O6S4 |
| Molecular Weight | 452.505 |
| Charge | -2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 3 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Lysine 539 of human band 3 is not essential for ion transport or inhibition by stilbene disulfonates. | 1989 Nov 25 |
|
| Antiviral immunotoxins: antibody-mediated delivery of gelonin inhibits Pichinde virus replication in vitro. | 1991 Feb |
|
| Stilbene disulfonic acids. CD4 antagonists that block human immunodeficiency virus type-1 growth at multiple stages of the virus life cycle. | 1991 Jul 15 |
|
| Inhibition of gp120-CD4 interaction and human immunodeficiency virus type 1 infection in vitro by pyridoxal 5'-phosphate. | 1994 Oct |
|
| Chromium- and nickel-induced cytotoxicity in normal and transformed human keratinocytes: an investigation of pharmacological approaches to the prevention of Cr(VI)-induced cytotoxicity. | 1996 Feb |
|
| Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds. | 1997 Sep-Oct |
|
| AE2 anion exchanger polypeptide is a homooligomer in pig gastric membranes: a chemical cross-linking study. | 1999 Jun 29 |
|
| Redox regulation of p53 during hypoxia. | 2000 Aug 10 |
|
| Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4. | 2000 Sep 29 |
|
| Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages. | 2002 Apr |
|
| Tumour-specific activation of the sodium/iodide symporter gene under control of the glucose transporter gene 1 promoter (GTI-1.3). | 2003 May |
|
| Effects of a new cystic fibrosis transmembrane conductance regulator inhibitor on Cl- conductance in human sweat ducts. | 2004 Jul |
|
| ATP binding cassette transporter ABC1 is required for the release of interleukin-1beta by P2X7-stimulated and lipopolysaccharide-primed mouse Schwann cells. | 2005 Mar |
|
| Ionic currents in multidrug resistant K562 human leukemic cells. | 2005 Sep |
|
| Absorption of folate by Caco-2 cells is not affected by high glucose concentration. | 2006 Dec 3 |
|
| Chronic high glucose inhibits albumin reabsorption by lysosomal alkalinization in cultured porcine proximal tubular epithelial cells (LLC-PK1). | 2006 Jun |
|
| Anion exchanger 2 mediates the action of arsenic trioxide. | 2006 Sep |
|
| Appearance of segmental discrepancy of anion transport in rat distal colon. | 2007 Aug |
|
| Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter. | 2007 Aug |
|
| Cloning and functional characterization of a folate transporter from the nematode Caenorhabditis elegans. | 2007 Aug |
|
| Activity and regulation of Na+-HCO3- cotransporter in immortalized spontaneously hypertensive rat and Wistar-Kyoto rat proximal tubular epithelial cells. | 2007 May |
|
| Functional ion channels in mouse bone marrow mesenchymal stem cells. | 2007 Nov |
|
| The volume-sensitive chloride channel inhibitors prevent both contractile dysfunction and apoptosis induced by doxorubicin through PI3kinase, Akt and Erk 1/2. | 2008 Jan |
|
| Pharmacologic blockade of chloride channel synergistically enhances apoptosis of chemotherapeutic drug-resistant cancer stem cells. | 2008 Sep 5 |
|
| Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. | 2009 Feb |
|
| Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis. | 2010 Dec |
|
| Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons. | 2010 Jan |
|
| Attenuating homologous recombination stimulates an AID-induced antileukemic effect. | 2013 May 6 |
|
| Functional swapping between transmembrane proteins TMEM16A and TMEM16F. | 2014 Mar 14 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 13:05:39 GMT 2023
by
admin
on
Sat Dec 16 13:05:39 GMT 2023
|
| Record UNII |
1VFRQ7416A
|
| Record Status |
Validated (UNII)
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| Record Version |
|
-
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5702690
Created by
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PRIMARY | |||
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1VFRQ7416A
Created by
admin on Sat Dec 16 13:05:39 GMT 2023 , Edited by admin on Sat Dec 16 13:05:39 GMT 2023
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132132-49-1
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admin on Sat Dec 16 13:05:39 GMT 2023 , Edited by admin on Sat Dec 16 13:05:39 GMT 2023
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67483-13-0
Created by
admin on Sat Dec 16 13:05:39 GMT 2023 , Edited by admin on Sat Dec 16 13:05:39 GMT 2023
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NON-SPECIFIC STEREOCHEMISTRY | |||
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344481
Created by
admin on Sat Dec 16 13:05:39 GMT 2023 , Edited by admin on Sat Dec 16 13:05:39 GMT 2023
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PRIMARY |