ONVATILIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:03:33 GMT 2023` Edited by `admin` on `Sat Dec 16 14:03:33 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	1UI8F5IIZ4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ONVATILIMAB

Official Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN PROTEIN VISTA (V-DOMAIN IMMUNOGLOBULIN SUPPRESSOR OF T CELL ACTIVATION)) (HUMAN CLONE JNJ 61610588 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN CLONE JNJ 61610588 .KAPPA.-CHAIN, DIMER

Systematic Name

English

JNJ61610588

Code

English

ONVATILIMAB [USAN]

Common Name

English

onvatilimab [INN]

Common Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION (PLATELET RECEPTOR GI24, SISP1))HUMAN MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (HOMO SAPIENS VH (IGHV1-69*01 (IGHD)-IGHJ4*01) (8.8.

Systematic Name

English

JNJ-61610588

Code

English

Code System Code Type Description

FDA UNII

1UI8F5IIZ4

Created by admin on Sat Dec 16 14:03:33 GMT 2023 , Edited by admin on Sat Dec 16 14:03:33 GMT 2023

PRIMARY

NCI_THESAURUS

C127124

Created by admin on Sat Dec 16 14:03:33 GMT 2023 , Edited by admin on Sat Dec 16 14:03:33 GMT 2023

PRIMARY

USAN

FG-97

Created by admin on Sat Dec 16 14:03:33 GMT 2023 , Edited by admin on Sat Dec 16 14:03:33 GMT 2023

PRIMARY

INN

10758

Created by admin on Sat Dec 16 14:03:33 GMT 2023 , Edited by admin on Sat Dec 16 14:03:33 GMT 2023

PRIMARY

CAS

1969313-51-6

Created by admin on Sat Dec 16 14:03:33 GMT 2023 , Edited by admin on Sat Dec 16 14:03:33 GMT 2023

PRIMARY

From	To
1_22	1_96
1_147	1_203
1_264	1_324
1_370	1_428
1_223	3_214
1_229	2_229
1_232	2_232
2_22	2_96
2_147	2_203
2_264	2_324
2_370	2_428
2_223	4_214
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					41TC1U8V3B

V-TYPE IMMUNOGLOBULIN DOMAIN-CONTAINING SUPPRESSOR OF T-CELL ACTIVATION

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					1UI8F5IIZ4

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL