Dalnicastobart

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 09:38:28 GMT 2025` Edited by `admin` on `Wed Apr 02 09:38:28 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	1SN6KFW31L
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Immunoglobulin G1 [de-236-glycine,de-C-terminal lysine], anti-(human CD40 antigen) (human monoclonal LVGN7409 ?1-chain), disulfide with human monoclonal LVGN7409 ?-chain, dimer

Preferred Name

English

Dalnicastobart

Official Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens CD40 (tumor necrosis factor receptor superfamily member 5, TNFRSF5, p50)], Homo sapiens monoclonal antibody, gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV1-2*02 (98.0%) -(IGHD) -IGHJ4*01 (100%)

Common Name

English

dalnicastobart [INN]

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C178278

Created by admin on Wed Apr 02 09:38:28 GMT 2025 , Edited by admin on Wed Apr 02 09:38:28 GMT 2025

PRIMARY

CAS

2642171-59-1

Created by admin on Wed Apr 02 09:38:28 GMT 2025 , Edited by admin on Wed Apr 02 09:38:28 GMT 2025

PRIMARY

FDA UNII

1SN6KFW31L

Created by admin on Wed Apr 02 09:38:28 GMT 2025 , Edited by admin on Wed Apr 02 09:38:28 GMT 2025

PRIMARY

SMS_ID

300000046856

Created by admin on Wed Apr 02 09:38:28 GMT 2025 , Edited by admin on Wed Apr 02 09:38:28 GMT 2025

PRIMARY

INN

12377

Created by admin on Wed Apr 02 09:38:28 GMT 2025 , Edited by admin on Wed Apr 02 09:38:28 GMT 2025

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_375	2_433
2_269	2_329
2_229	4_214
2_153	2_209
2_105	2_110
2_22	2_96
1_375	1_433
1_269	1_329
1_238	2_238
1_235	2_235
1_229	3_214
1_153	1_209
1_105	1_110
1_22	1_96

Glycosylation Link Type	Site
N	1_305
N	2_305

Related Record Type Details


					1SN6KFW31L

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]			Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL