3,3'-DICHLOROBENZIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H10Cl2N2
Molecular Weight	253.127
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=CC=C(C=C1Cl)C2=CC(Cl)=C(N)C=C2

InChI

InChIKey=HUWXDEQWWKGHRV-UHFFFAOYSA-N

InChI=1S/C12H10Cl2N2/c13-9-5-7(1-3-11(9)15)8-2-4-12(16)10(14)6-8/h1-6H,15-16H2

HIDE SMILES / InChI

Molecular Formula	C12H10Cl2N2
Molecular Weight	253.127
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Experimental neoplasia in rats from oral administration of 3,3'-dichlorobenzidine, 4,4'-methylene-bis-bis(2-chloroaniline), and 4,4'-methylene-bis(2-methylaniline).	1975 Jan	1129785
Activation of 3,3'-dichlorobenzidine in rat liver microsomes to mutagens: involvement of cytochrome P-450d.	1988 May	3130202
Mutagenic activation of urinary bladder carcinogens by CYP4B1 and the presence of CYP4B1 in bladder mucosa.	1997 Sep 15	9310344
Using base-specific Salmonella tester strains to characterize the types of mutation induced by benzidine and benzidine congeners after reductive metabolism.	2001 Dec	11696399
[Resolution of overlapping mass spectra of azobiphenyl dyes by subwindow factor analysis technique].	2001 Mar	12541672
3,3'-Dichlorobenzidine and 3,3'-dichlorobenzidine dihydrochloride.	2002	15323034
Identification of a new mutagenic polychlorinated biphenyl derivative in the Waka River, Wakayama, Japan, showing activation of an aryl hydrocarbon receptor-dependent transcription.	2002 Mar	11896690
Photodechlorination of 3,3'-dichlorobenzidine in water.	2002 Mar	11878462
Determination of hemoglobin adducts formed in rats exposed orally with 3,3'-dichlorobenzidine by GC/MS-SIM.	2002 May	12974542
Transport behavior of 3,3'-dichlorobenzidine in a freshwater estuary.	2003 Jan	12503742
Synthesis and evaluation of analogues of Congo red as potential compounds against transmissible spongiform encephalopathies.	2003 Jun	12832128
Concentrations and distribution of 3,3'-dichlorobenzidine and its congeners in environmental samples from Lake Macatawa.	2005 Feb	15621190
Sorption of benzidine and 3,3'-dichlorobenzidine to lake sediments. 1. Conceptualization and development of a multiparameter model.	2005 May	16110977
Evaluation of urinary mutagenicity in azo dye manufacture workers.	2007	17638680
Induction of SCEs in CHL cells by dichlorobiphenyl derivative water pollutants, 2-phenylbenzotriazole (PBTA) congeners and river water concentrates.	2009 Aug	19545646

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:41:43 GMT 2023` Edited by `admin` on `Fri Dec 15 17:41:43 GMT 2023`
Record UNII	1SDI2328UX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

3,3'-DICHLOROBENZIDINE

Systematic Name

English

DICHLOROBENZIDINE, 3,3'-

Systematic Name

English

3,3'-DICHLORO-(1,1'-BIPHENYL)-4,4'-DIAMINE

Systematic Name

English

3,3'-DICHLORO-4,4'-BIPHENYLDIAMINE

Systematic Name

English

3,3'-DICHLOROBENZIDINE [HSDB]

Common Name

English

3,3'-DICHLOROBENZIDINE [IARC]

Common Name

English

NSC-154073

Code

English

DCB

Common Name

English

3,3'-DICHLOROBENZIDINE [MI]

Common Name

English

Code System Code Type Description

FDA UNII

1SDI2328UX