2,4-DIAMINO-6-HYDROXYMETHYLPTERIDINE

NC1=NC(N)=C2N=C(CO)C=NC2=N1

InChIKey=CYNARAWTVHQHDI-UHFFFAOYSA-N

InChI=1S/C7H8N6O/c8-5-4-6(13-7(9)12-5)10-1-3(2-14)11-4/h1,14H,2H2,(H4,8,9,10,12,13)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds.	1999 Aug 26	10464017
Design, synthesis, computational prediction, and biological evaluation of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii.	2001 Jul 19	11448221
Photohydrolysis of methotrexate produces pteridine, which induces poly-G-specific DNA damage through photoinduced electron transfer.	2002 Nov	12462639
Determination of the chiral and achiral related substances of methotrexate by cyclodextrin-modified micellar electrokinetic chromatography.	2004 Aug	15352016
Prediction of genotoxicity of chemical compounds by statistical learning methods.	2005 Jun	15962942
Plasmodium berghei: lack of antimalarial activity of an analogue of folate precursor, 2,4-diamino-6-hydroxymethylpteridine in a mouse model.	2008 Nov	18789931

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:04:57 GMT 2023` Edited by `admin` on `Sat Dec 16 08:04:57 GMT 2023`
Record UNII	1RU16O4RO0
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

2,4-DIAMINO-6-HYDROXYMETHYLPTERIDINE

Systematic Name

English

6-PTERIDINEMETHANOL, 2,4-DIAMINO-

Systematic Name

English

(2,4-DIAMINOPTERIDIN-6-YL)METHANOL

Systematic Name

English

METHOTREXATE IMPURITY A [EP IMPURITY]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID10915479