TECHNETIUM TC-99M ETIFENIN

First approved in 1973

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C16H20N2O5.Tc.H
Molecular Weight	740.595
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H+].[99Tc+3].CCC1=CC=CC(CC)=C1NC(=O)CN(CC([O-])=O)CC([O-])=O.CCC2=CC=CC(CC)=C2NC(=O)CN(CC([O-])=O)CC([O-])=O

InChI

InChIKey=UWBDZLSLZZGHFD-FCHARDOESA-K

InChI=1S/2C16H22N2O5.Tc/c2*1-3-11-6-5-7-12(4-2)16(11)17-13(19)8-18(9-14(20)21)10-15(22)23;/h2*5-7H,3-4,8-10H2,1-2H3,(H,17,19)(H,20,21)(H,22,23);/q;;+3/p-3/i;;1+1

HIDE SMILES / InChI

Molecular Formula	C16H20N2O5
Molecular Weight	320.3404
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H
Molecular Weight	1.0079
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Tc
Molecular Weight	98.9063
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2578
bone problems 43 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8429	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 43 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8429	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012 Oct	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:18:17 GMT 2023` Edited by `admin` on `Sat Dec 16 08:18:17 GMT 2023`
Record UNII	1R72G5JPE8
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

TECHNETIUM TC-99M ETIFENIN

Common Name

English

TECHNETIUM (99MTC) ETIFENIN INJECTION [EP IMPURITY]

Common Name

English

TECHNETIUM (99MTC) ETIFENIN

Common Name

English

TECHNETIUM (99M TC) ETIFENIN

Common Name

English

GLYCINE, N-(CARBOXYMETHYL)-N-(2-((2,6-DIETHYLPHENYL)AMINO)-2-OXOETHYL)-, TECHNETIUM-99M COMPLEX

Common Name

English

TC-99M EHIDA

Common Name

English

Technetium (99m tc) etifenin [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-ATC

V09DA02