U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:03:52 GMT 2023
Edited
by admin
on Sat Dec 16 14:03:52 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
1Q2QT5M7EO
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BALSTILIMAB
USAN   INN  
Official Name English
Balstilimab [WHO-DD]
Common Name English
ANTI-PD1 MONOCLONAL ANTIBODY AGEN2034
Common Name English
A FULLY HUMAN IGG4 MONOCLONAL ANTAGONIST ANTIBODY DIRECTED AGAINST PROGRAMME D CELL DEATH PROTEIN 1 (PD-1) WITH POTENTIAL IMMUNE CHECKPOINT INHIBITORY AND ANTINEOPLASTIC ACTIVITIES
Common Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMAN MONOCLONAL AGEN2034 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AGEN2034 .KAPPA.-CHAIN, DIMER
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), HOMO SAPIENS MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN HOMO SAPIENS (1-440) (VH (HOMO SAPIENS IGHV3-33*01 (100%)-(IGHD)-IGHJ1*01 (100%)) (8.8.6) (1-113)-HOMO SAPI
Common Name English
AGEN2034
Code English
AGEN-2034
Code English
balstilimab [INN]
Common Name English
BALSTILIMAB [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C128037
Created by admin on Sat Dec 16 14:03:52 GMT 2023 , Edited by admin on Sat Dec 16 14:03:52 GMT 2023
NCI_THESAURUS C129822
Created by admin on Sat Dec 16 14:03:52 GMT 2023 , Edited by admin on Sat Dec 16 14:03:52 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C136465
Created by admin on Sat Dec 16 14:03:52 GMT 2023 , Edited by admin on Sat Dec 16 14:03:52 GMT 2023
PRIMARY
DRUG BANK
DB15676
Created by admin on Sat Dec 16 14:03:52 GMT 2023 , Edited by admin on Sat Dec 16 14:03:52 GMT 2023
PRIMARY
CAS
2230167-06-1
Created by admin on Sat Dec 16 14:03:52 GMT 2023 , Edited by admin on Sat Dec 16 14:03:52 GMT 2023
NO STRUCTURE GIVEN
USAN
HI-66
Created by admin on Sat Dec 16 14:03:52 GMT 2023 , Edited by admin on Sat Dec 16 14:03:52 GMT 2023
PRIMARY
FDA UNII
1Q2QT5M7EO
Created by admin on Sat Dec 16 14:03:52 GMT 2023 , Edited by admin on Sat Dec 16 14:03:52 GMT 2023
PRIMARY
INN
10993
Created by admin on Sat Dec 16 14:03:52 GMT 2023 , Edited by admin on Sat Dec 16 14:03:52 GMT 2023
PRIMARY
CAS
2148321-77-9
Created by admin on Sat Dec 16 14:03:52 GMT 2023 , Edited by admin on Sat Dec 16 14:03:52 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_127 4_214
2_140 2_196
2_254 2_314
1_127 3_214
2_360 2_418
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_140 1_196
1_219 2_219
1_222 2_222
1_254 1_314
1_360 1_418
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_290
N 2_290
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL