BALSTILIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 22:06:29 GMT 2025` Edited by `admin` on `Tue Apr 01 22:06:29 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	1Q2QT5M7EO
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BALSTILIMAB

Official Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), HOMO SAPIENS MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN HOMO SAPIENS (1-440) (VH (HOMO SAPIENS IGHV3-33*01 (100%)-(IGHD)-IGHJ1*01 (100%)) (8.8.6) (1-113)-HOMO SAPI

Preferred Name

English

Balstilimab [WHO-DD]

Common Name

English

ANTI-PD1 MONOCLONAL ANTIBODY AGEN2034

Common Name

English

A FULLY HUMAN IGG4 MONOCLONAL ANTAGONIST ANTIBODY DIRECTED AGAINST PROGRAMME D CELL DEATH PROTEIN 1 (PD-1) WITH POTENTIAL IMMUNE CHECKPOINT INHIBITORY AND ANTINEOPLASTIC ACTIVITIES

Common Name

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMAN MONOCLONAL AGEN2034 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AGEN2034 .KAPPA.-CHAIN, DIMER

Common Name

English

AGEN2034

Code

English

AGEN-2034

Code

English

balstilimab [INN]

Common Name

English

BALSTILIMAB [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C128037

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

NCI_THESAURUS

C129822

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

Code System Code Type Description

SMS_ID

100000183978

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

PRIMARY

NCI_THESAURUS

C136465

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

PRIMARY

DRUG BANK

DB15676

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

PRIMARY

CAS

2230167-06-1

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

NO STRUCTURE GIVEN

USAN

HI-66

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

PRIMARY

FDA UNII

1Q2QT5M7EO

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

PRIMARY

INN

10993

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

PRIMARY

CAS

2148321-77-9

Created by admin on Tue Apr 01 22:06:29 GMT 2025 , Edited by admin on Tue Apr 01 22:06:29 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_127	4_214
2_140	2_196
2_254	2_314
1_127	3_214
2_360	2_418
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_140	1_196
1_219	2_219
1_222	2_222
1_254	1_314
1_360	1_418

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_290
N	2_290

Related Record Type Details


					938DNF64FO

PROGRAMMED CELL DEATH PROTEIN 1

TARGET -> INHIBITOR

Related Record Type Details


					1Q2QT5M7EO

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL