U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 18:25:40 GMT 2025
Edited
by admin
on Mon Mar 31 18:25:40 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
1P48L61KM0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMG-655
Preferred Name English
CONATUMUMAB
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
conatumumab [INN]
Common Name English
Conatumumab [WHO-DD]
Common Name English
TRAIL-R2 MAB
Code English
AN MONOCLONAL XG1-048 (ARG(SUP 219),GLU(SUP 361),MET(SUP 363)).GAMMA.1 HEAVY CHAIN (225-215')-DISULPHIDE WITH .KAPPA. LIGHT CHAIN (231-231'':234-234'')-BISDISULPHIDE DIMER
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B (DEATH RECEPTOR 5, TRAIL-R2, CD262 ANTIGEN))
Common Name English
AMG 655
Code English
XG1-048
Code English
CONATUMUMAB [USAN]
Common Name English
AN MONOCLONAL XG1-048 (ARG(SUP 219),GLU(SUP 361),MET(SUP 363)).GAMMA.1 HEAVY CHAIN (225-215')-DISULFIDE WITH .KAPPA. LIGHT CHAIN (231-231'':234-234'')-BISDISULFIDE DIMER
Common Name English
TRAIL-R2-MAB
Code English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
NCI_THESAURUS C129822
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
Code System Code Type Description
CAS
896731-82-1
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
DRUG BANK
DB11646
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
FDA UNII
1P48L61KM0
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
INN
9029
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
ChEMBL
CHEMBL1743003
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
SMS_ID
100000141688
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
NCI_THESAURUS
C71015
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
WIKIPEDIA
CONATUMUMAB
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
USAN
TT-66
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
EVMPD
SUB96119
Created by admin on Mon Mar 31 18:25:40 GMT 2025 , Edited by admin on Mon Mar 31 18:25:40 GMT 2025
PRIMARY
From To
1_22 1_97
2_22 2_97
3_23 3_89
4_23 4_89
3_135 3_195
4_135 4_195
1_149 1_205
2_149 2_205
1_225 3_215
2_225 4_215
1_231 2_231
1_234 2_234
1_266 1_326
2_266 2_326
1_372 1_430
2_372 2_430
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_302
N 2_302
Related Record Type Details
TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B
TARGET -> AGONIST
Related Record Type Details
CONATUMUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:ESTIMATED CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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