U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:12:26 GMT 2023
Edited
by admin
on Sat Dec 16 14:12:26 GMT 2023
Protein Sub Type
Record UNII
1OHI4ZB7S1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1
Common Name English
MTORC1 (CONTAINS MTOR, MLST8, RPTOR, AKT1S1/PRAS40 AND DEPTOR DIMER OF TWO STOICHIOMETRIC HETEROTETRAMERS)
Common Name English
MTORC1
Common Name English
Code System Code Type Description
FDA UNII
1OHI4ZB7S1
Created by admin on Sat Dec 16 14:12:27 GMT 2023 , Edited by admin on Sat Dec 16 14:12:27 GMT 2023
PRIMARY
UNIPROT
Q8TB45
Created by admin on Sat Dec 16 14:12:27 GMT 2023 , Edited by admin on Sat Dec 16 14:12:27 GMT 2023
MAJOR COMPONENT STRUCTURE/SEQUENCE
UNIPROT
Q96B36
Created by admin on Sat Dec 16 14:12:27 GMT 2023 , Edited by admin on Sat Dec 16 14:12:27 GMT 2023
MAJOR COMPONENT STRUCTURE/SEQUENCE
UNIPROT
P42345
Created by admin on Sat Dec 16 14:12:27 GMT 2023 , Edited by admin on Sat Dec 16 14:12:27 GMT 2023
MAJOR COMPONENT STRUCTURE/SEQUENCE
Related Record Type Details
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Significantly suppresses fluid endocytosis and bead/bacterial phagocytosis during TPA-induced differentiation, but not in undifferentiated THP-1 cells.
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INHIBITOR -> TARGET
Bisteric inhibitor of Ribosomal protein S6 kinase beta-1 and eukaryotic initiation factor 4E-binding protein 1 phosphorylation.
IN-VITRO
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INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL