Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H19N3.3ClH |
| Molecular Weight | 254.629 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.Cl.NCCCCNCCCN
InChI
InChIKey=LCNBIHVSOPXFMR-UHFFFAOYSA-N
InChI=1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
| Molecular Formula | C7H19N3 |
| Molecular Weight | 145.2459 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| S-adenosylmethionine decarboxylase overexpression reduces invasiveness and tumorigenicity in nude mice of MCF-7 breast cancer cells. | 2001-08 |
|
| Regional distribution of ornithine decarboxylase activity and polyamine levels in experimental cat brain tumors. | 2001-08 |
|
| Significance of asymmetric sites in choosing siderophores as deferration agents. | 2001-07-19 |
|
| Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives. | 2001-07-19 |
|
| Polyamines regulate gap junction communication in connexin 43-expressing cells. | 2001-07-15 |
|
| Raman study of the interaction between polyamines and a GC oligonucleotide. | 2001-07-13 |
|
| Inhibitory effects on HIV-1 protease of tri-p-coumaroylspermidine from Artemisia caruifolia and related amides. | 2001-07 |
|
| Changes in polyamines, auxins and peroxidase activity during in vitro rooting of Fraxinus angustifolia shoots: an auxin-independent rooting model. | 2001-07 |
|
| A barley polyamine oxidase isoform with distinct structural features and subcellular localization. | 2001-07 |
|
| Genetic analysis of spermidine synthase from Leishmania donovani. | 2001-07 |
|
| Ovothiol and trypanothione as antioxidants in trypanosomatids. | 2001-07 |
|
| Polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry. | 2001-07 |
|
| Polyamine depletion arrests growth of IEC-6 and Caco-2 cells by different mechanisms. | 2001-07 |
|
| Occurrence of cadaverine in hairy roots of Brugmansia candida. | 2001-07 |
|
| The early stages of filamentous phage phiLf infection require the host transcription factor, Clp. | 2001-07 |
|
| Intra-amygdala spermidine administration improves inhibitory avoidance performance in rats. | 2001-06-29 |
|
| Polyamine uptake systems in Escherichia coli. | 2001-06-26 |
|
| Polyamine synthesis and interconversion by the Microsporidian Encephalitozoon cuniculi. | 2001-06-20 |
|
| Inhibition by interferon alpha-2b of rat liver regeneration: effect on ornithine decarboxylase and total protein synthesis. | 2001-06-15 |
|
| Molecular umbrella-assisted transport of glutathione across a phospholipid membrane. | 2001-06-13 |
|
| Chemoprevention by difluoromethylornithine: correlation of an in vitro human cell assay with human clinical data for biomarker modulation. | 2001-06-09 |
|
| Determination of polyamines in human saliva by high-performance liquid chromatography with fluorescence detection. | 2001-06-05 |
|
| Importance of the 3' untranslated region of ornithine decarboxylase mRNA in the translational regulation of the enzyme. | 2001-06-01 |
|
| A monoclonal antibody against the glutaraldehyde-conjugated polyamine, putrescine: application to immunocytochemistry. | 2001-06 |
|
| Polyamines: new cues in cellular signal transduction. | 2001-06 |
|
| Agmatine and putrescine uptake in the human glioma cell line SK-MG-1. | 2001-06 |
|
| Permeability characteristics of polyamines across intestinal epithelium using the Caco-2 monolayer system: comparison between transepithelial flux and mitogen-stimulated uptake into epithelial cells. | 2001-06 |
|
| Disappearance of the negative charge in giant DNA with a folding transition. | 2001-06 |
|
| Polyamines in the basal ganglia of human brain. Influence of aging and degenerative movement disorders. | 2001-05-18 |
|
| Guanidino-containing drugs in cancer chemotherapy: biochemical and clinical pharmacology. | 2001-05-15 |
|
| Structure-function studies of human deoxyhypusine synthase: identification of amino acid residues critical for the binding of spermidine and NAD. | 2001-05-01 |
|
| Effects of DL111-IT or combined with RU486 on uterine polyamines biosynthesis in rats during early gestation. | 2001-05 |
|
| Establishment and characterization of cell-free translation/glycosylation in insect cell (Spodoptera frugiperda 21) extract prepared with high pressure treatment. | 2001-05 |
|
| Inactivation of catalase and superoxide dismutase by singlet oxygen derived from photoactivated dye. | 2001-05 |
|
| Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N-acetyltransferase. | 2001-05 |
|
| Cellular pharmacodynamics of the cytotoxic guanidino-containing drug CHS 828. Comparison with methylglyoxal-bis(guanylhydrazone). | 2001-04-20 |
|
| Effect of the interaction between a low tyramine-producing Lactobacillus and proteolytic staphylococci on biogenic amine production during ripening and storage of dry sausages. | 2001-04-11 |
|
| Intestinal ornithine decarboxylase in short bowel syndrome patients with oral diet. | 2001-04 |
|
| Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells. | 2001-03-29 |
|
| Polyamines secreted by cancer cells possibly account for the impairment of the human erythrocyte sodium pump activity. | 2001-03 |
|
| Structures of tryparedoxins revealing interaction with trypanothione. | 2001-03 |
|
| X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid. | 2001-03 |
|
| A mammalian sequence-dependent upstream open reading frame mediates polyamine-regulated translation in yeast. | 2001-03 |
|
| Phosphodiester and phosphorothioate oligonucleotide condensation and preparation of antisense nanoparticles. | 2001-01-12 |
|
| Alteration in expression of the rat mitochondrial ATPase 6 gene during Pneumocystis carinii infection. | 2001 |
|
| Concomitant down-regulation of L-arginine transport and nitric oxide (NO) synthesis in rat alveolar macrophages by the polyamine spermine. | 2001 |
|
| Extracting biological information from DNA arrays: an unexpected link between arginine and methionine metabolism in Bacillus subtilis. | 2001 |
|
| Specific peptide inhibitors of trypanothione reductase with backbone structures unrelated to that of substrate: potential rational drug design lead frameworks. | 2001 |
|
| Polyamines of the thermophilic eubacteria belonging to the genera Thermosipho, Thermaerobacter and Caldicellulosiruptor. | 2001 |
|
| Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse. | 2001 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:01:05 GMT 2025
by
admin
on
Mon Mar 31 21:01:05 GMT 2025
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| Record UNII |
1O14BED398
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| Record Status |
Validated (UNII)
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| Record Version |
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334-50-9
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206-379-0
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DTXSID0059825
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1O14BED398
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m10139
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528399
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9539
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PARENT -> SALT/SOLVATE |
