ORILANOLIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:20:24 UTC 2023` Edited by `admin` on `Sat Dec 16 14:20:24 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	1LTT6HMX9N
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ORILANOLIMAB

Official Name

English

SYNT-001

Code

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN FCRN RECEPTOR) (HUMANIZED MONOCLONAL SYNT001 .GAMMA.4-CHAIN), DISULFIDE WITH HUMANIZED MONOCLONAL SYNT001 .KAPPA.-CHAIN, DIMER

Common Name

English

ORILANOLIMAB [USAN]

Common Name

English

ALXN-1830

Code

English

ALXN1830

Code

English

orilanolimab [INN]

Common Name

English

SYNT001

Code

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS IGG RECEPTOR FCRN LARGE SUBUNIT P51; SHORT=FCRN (NEONATAL FC RECEPTOR)); HUMANIZED MOUSE MONOCLONAL ANTIBODY; .GAMMA.4 HEAVY CHAIN (1-444) (VH (MUS MUSCULUS IGHV1-81*01 (93%) (IGHD)-IGHJ1*03 (92%)/HOMO SAPIENS

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

649018

Created by admin on Sat Dec 16 14:20:24 UTC 2023 , Edited by admin on Sat Dec 16 14:20:24 UTC 2023

Code System Code Type Description

DRUG BANK

DB15312

Created by admin on Sat Dec 16 14:20:24 UTC 2023 , Edited by admin on Sat Dec 16 14:20:24 UTC 2023

PRIMARY

USAN

JK-19

Created by admin on Sat Dec 16 14:20:24 UTC 2023 , Edited by admin on Sat Dec 16 14:20:24 UTC 2023

PRIMARY

CAS

2066544-85-0

Created by admin on Sat Dec 16 14:20:24 UTC 2023 , Edited by admin on Sat Dec 16 14:20:24 UTC 2023

PRIMARY

INN

10825

Created by admin on Sat Dec 16 14:20:24 UTC 2023 , Edited by admin on Sat Dec 16 14:20:24 UTC 2023

PRIMARY

FDA UNII

1LTT6HMX9N

Created by admin on Sat Dec 16 14:20:24 UTC 2023 , Edited by admin on Sat Dec 16 14:20:24 UTC 2023

PRIMARY

NCI_THESAURUS

C139561

Created by admin on Sat Dec 16 14:20:24 UTC 2023 , Edited by admin on Sat Dec 16 14:20:24 UTC 2023

PRIMARY

From	To
1_22	1_96
1_145	1_201
1_259	1_319
1_365	1_423
1_132	3_214
1_224	2_224
1_227	2_227
2_22	2_96
2_145	2_201
2_259	2_319
2_365	2_423
2_132	4_214
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194

Glycosylation Link Type	Site
N	1_295
N	2_295

Related Record Type Details


					TW3XAW0RCY

NEONATAL FC RECEPTOR

TARGET -> INHIBITOR

Related Record Type Details


					1LTT6HMX9N

ACTIVE MOIETY

Comments:

immunomodulator

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL