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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 23:12:16 GMT 2025
Edited
by admin
on Tue Apr 01 23:12:16 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
1LTT6HMX9N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ORILANOLIMAB
INN   USAN  
Official Name English
ALXN-1830
Preferred Name English
SYNT-001
Code English
IMMUNOGLOBULIN G4, ANTI-(HUMAN FCRN RECEPTOR) (HUMANIZED MONOCLONAL SYNT001 .GAMMA.4-CHAIN), DISULFIDE WITH HUMANIZED MONOCLONAL SYNT001 .KAPPA.-CHAIN, DIMER
Common Name English
ORILANOLIMAB [USAN]
Common Name English
ALXN1830
Code English
orilanolimab [INN]
Common Name English
SYNT001
Code English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS IGG RECEPTOR FCRN LARGE SUBUNIT P51; SHORT=FCRN (NEONATAL FC RECEPTOR)); HUMANIZED MOUSE MONOCLONAL ANTIBODY; .GAMMA.4 HEAVY CHAIN (1-444) (VH (MUS MUSCULUS IGHV1-81*01 (93%) (IGHD)-IGHJ1*03 (92%)/HOMO SAPIENS
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 649018
Created by admin on Tue Apr 01 23:12:16 GMT 2025 , Edited by admin on Tue Apr 01 23:12:16 GMT 2025
Code System Code Type Description
DRUG BANK
DB15312
Created by admin on Tue Apr 01 23:12:16 GMT 2025 , Edited by admin on Tue Apr 01 23:12:16 GMT 2025
PRIMARY
USAN
JK-19
Created by admin on Tue Apr 01 23:12:16 GMT 2025 , Edited by admin on Tue Apr 01 23:12:16 GMT 2025
PRIMARY
CAS
2066544-85-0
Created by admin on Tue Apr 01 23:12:16 GMT 2025 , Edited by admin on Tue Apr 01 23:12:16 GMT 2025
PRIMARY
INN
10825
Created by admin on Tue Apr 01 23:12:16 GMT 2025 , Edited by admin on Tue Apr 01 23:12:16 GMT 2025
PRIMARY
FDA UNII
1LTT6HMX9N
Created by admin on Tue Apr 01 23:12:16 GMT 2025 , Edited by admin on Tue Apr 01 23:12:16 GMT 2025
PRIMARY
NCI_THESAURUS
C139561
Created by admin on Tue Apr 01 23:12:16 GMT 2025 , Edited by admin on Tue Apr 01 23:12:16 GMT 2025
PRIMARY
SMS_ID
100000183535
Created by admin on Tue Apr 01 23:12:16 GMT 2025 , Edited by admin on Tue Apr 01 23:12:16 GMT 2025
PRIMARY
From To
1_22 1_96
1_145 1_201
1_259 1_319
1_365 1_423
1_132 3_214
1_224 2_224
1_227 2_227
2_22 2_96
2_145 2_201
2_259 2_319
2_365 2_423
2_132 4_214
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Link Type Site
N 1_295
N 2_295
Related Record Type Details
NEONATAL FC RECEPTOR
TARGET -> INHIBITOR
Related Record Type Details
ORILANOLIMAB
ACTIVE MOIETY
immunomodulator
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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