U.S. Department of Health & Human Services
National Institutes of Health
NCATS
This repository is under review for potential modification in compliance with Administration directives.
Dismiss
Return Home
Inxight
Drugs
Search Substances
Home
Browse Drugs
US Approved Drugs
Marketed Drugs
Investigational Drugs
All Substances
Search
Structure Search
Sequence Search
Downloads
About
Search Substances
S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2
1LM9SS1UEA
Possibly Marketed Outside US
First approved in 2019
General
Record Details
Names
5
Identifiers
3
Subunits
1
Relationships
2
Modifications
3
Characteristic Attributes
2
S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2
1LM9SS1UEA
Possibly Marketed Outside US
First approved in 2019
General
Approval Year
2019
334
Record Details
Substance Class
Protein
Protein Sub Type
Record UNII
1LM9SS1UEA
Record Status
Validated (UNII)
Record Version
16
15
14
13
12
11
10
9
8
7
6
5
4
3
2
1
Names
5
Show
5
20
100
All
entries
Name
Type
Language
Name
Type
Language
ADOMET SYNTHASE 2
Preferred Name
English
S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2
Common Name
English
METHIONINE ADENOSYLTRANSFERASE II
Common Name
English
MAT2A
Common Name
English
METHIONINE ADENOSYLTRANSFERASE II ALPHA
Common Name
English
Showing 1 to 5 of 5 entries
Previous
1
Next
Identifiers
3
Show
5
20
100
All
entries
Code System
Code
Type
Description
Code System
Code
Type
Description
DAILYMED
1LM9SS1UEA
PRIMARY
FDA UNII
1LM9SS1UEA
PRIMARY
RXCUI
2262277
PRIMARY
Showing 1 to 3 of 3 entries
Previous
1
Next
Subunits
1
Subunit 0
>SUBUNIT_0
Relationships
2
Show
5
20
100
All
entries
Related Record
Type
Details
Related Record
Type
Details
E1P2TDU69L
AG-270
INHIBITOR -> TARGET
Qualification:
IC50
Amount:
14 NANOMOLAR (average)
AZG477HC22
AG-270 Hydrochloride
INHIBITOR -> TARGET
Amount:
Showing 1 to 2 of 2 entries
Previous
1
Next
Modifications
3
Structural Modifications
Show
5
20
100
All
entries
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
AMINO_ACID_SUBSTITUTION
[1_81]
SITE_SPECIFIC
N6-ACETYLLYSINE
470AD5VY1X
METAL_BINDING
[1_31]
SITE_SPECIFIC
MAGNESIUM CATION
T6V3LHY838
METAL_BINDING
[1_57]
SITE_SPECIFIC
POTASSIUM CATION
295O53K152
Showing 1 to 3 of 3 entries
Previous
1
Next
Characteristic Attributes
2
Show
5
20
100
All
entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 43600 Da (average)
Molecular Formula
CHEMICAL
ESTIMATED
C1943H3058N537O583S12
Showing 1 to 2 of 2 entries
Previous
1
Next
