ANAPLASTIC LYMPHOMA KINASE C1156Y

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 23:55:35 GMT 2025` Edited by `admin` on `Tue Apr 01 23:55:35 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type	TYROSINE KINASE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	1L250UVH21
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ANAPLASTIC LYMPHOMA KINASE C1156Y

Common Name

English

CD-246 C1156Y

Preferred Name

English

ALK TYROSINE KINASE RECEPTOR C1156Y

Systematic Name

English

ALK C1156Y MUTANT

Common Name

English

CD246 C1156Y

Code

English

Code System Code Type Description

WIKIPEDIA

ANAPLASTIC LYMPHOMA KINASE

Created by admin on Tue Apr 01 23:55:35 GMT 2025 , Edited by admin on Tue Apr 01 23:55:35 GMT 2025

PRIMARY

EC (ENZYME CLASS)

EC 2.7.10.1

Created by admin on Tue Apr 01 23:55:35 GMT 2025 , Edited by admin on Tue Apr 01 23:55:35 GMT 2025

PRIMARY

FDA UNII

1L250UVH21

Created by admin on Tue Apr 01 23:55:35 GMT 2025 , Edited by admin on Tue Apr 01 23:55:35 GMT 2025

PRIMARY

UNIPROT

Q9UM73

Created by admin on Tue Apr 01 23:55:35 GMT 2025 , Edited by admin on Tue Apr 01 23:55:35 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_151
N	1_226
N	1_267
N	1_306
N	1_393
N	1_406
N	1_427
N	1_545
N	1_553
N	1_609
N	1_691
N	1_790
N	1_845
N	1_846
N	1_868
N	1_968

Related Record Type Details


					OSP71S83EU

LORLATINIB

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					Z5F65W1YAZ

IRUPLINALKIB

INHIBITOR -> TARGET

Qualification:

IC50

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_1060] [1_1074] [1_1078] [1_1113] [1_1260] [1_1489] [1_1586]				TYROSINE O-PHOSPHATE	2R86C98KDX

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL