Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H10S |
| Molecular Weight | 198.283 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C1C2=CC=CC=C2SC3=C1C=CC=C3
InChI
InChIKey=PQJUJGAVDBINPI-UHFFFAOYSA-N
InChI=1S/C13H10S/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12/h1-8H,9H2
| Molecular Formula | C13H10S |
| Molecular Weight | 198.283 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Zuclopenthixol acetate in the treatment of acute schizophrenia and similar serious mental illnesses. | 2001 |
|
| Zuclopenthixol treatment of behavioral disturbances in mentally retarded children and adolescents: an open-label study. | 2001 Fall |
|
| Nucleoside analogues as highly potent and selective inhibitors of herpes simplex virus thymidine kinase. | 2001 Jul 9 |
|
| DNA-dependent protein kinase is inhibited by trifluoperazine. | 2001 May 18 |
|
| Flow-injection chemiluminometric determination of some thioxanthene derivatives in pharmaceutical formulations and biological fluids using the [Ru(dipy)3(2+)]-Ce(IV) system. | 2001 Nov |
|
| Long-term effects of the substituted benzamide derivative amisulpride on baseline and stimulated prolactin levels. | 2002 |
|
| Inhibition of butyrylcholinesterase by phenothiazine derivatives. | 2002 Jun |
|
| Priapism associated with zuclopenthixol. | 2002 Jun |
|
| Separation of cis- and trans-isomers of thioxanthene and dibenz[b,e]oxepin derivatives on calixarene- and resorcinarene-bonded high-performance liquid chromatography stationary phases. | 2002 Mar 1 |
|
| New approach to biomimetic transamination using bifunctional [1,3]-proton transfer catalysis in thioxanthenyl dioxide imines. | 2002 May 31 |
|
| The glutathione-activated thiopurine prodrugs trans-6-(2-acetylvinylthio)guanine and cis-6-(2-acetylvinylthio)purine cause less in vivo toxicity than 6-thioguanine after single- and multiple-dose regimens. | 2002 Nov |
|
| S-pixyl analogues as photocleavable protecting groups for nucleosides. | 2002 Nov 1 |
|
| Platelet serotonin transporter in schizophrenic patients with and without neuroleptic treatment. | 2002 Oct |
|
| Flupenthixol in relapse prevention in schizophrenics with comorbid alcoholism: results from an open clinical study. | 2003 Apr |
|
| Overcrowded 1,8-diazafluorenylidene-chalcoxanthenes. Introducing nitrogens at the fjord regions of bistricyclic aromatic enes. | 2003 Aug 7 |
|
| Zuclopenthixol facilitates memory retrieval in rats: possible involvement of noradrenergic and serotonergic mechanisms. | 2003 Jul |
|
| Distinct tissue distribution of metabolites of the novel glutathione-activated thiopurine prodrugs cis-6-(2-acetylvinylthio)purine and trans-6-(2-acetylvinylthio)guanine and 6-thioguanine in the mouse. | 2003 Jun |
|
| Separation of (Z)- and (E)-isomers of thioxanthene and dibenz[b,e]oxepin derivatives with calixarenes and resorcinarenes as additives in nonaqueous capillary electrophoresis. | 2003 May |
|
| Allosteric modulation of human P-glycoprotein. Inhibition of transport by preventing substrate translocation and dissociation. | 2003 May 16 |
|
| Twin-rotor system created on a [4]radialene frame. | 2003 Sep 18 |
|
| A novel two-carbon homologation with N-vinylacetamides and ethyl vinyl ether as acetaldehyde anion equivalents in the synthesis of 9H-xanthene, 9H-thioxanthene, and 9,10-dihydro-9-acridine carboxaldehydes. | 2004 Jan 23 |
|
| Thioxanthene-derived analogs as sigma(1) receptor ligands. | 2004 May 3 |
|
| Determination of mercaptopurine and its four metabolites by large-volume sample stacking with polarity switching in capillary electrophoresis. | 2005 Jun |
|
| A system for precise analysis of transcription-regulating elements of immunoglobulin genes. | 2005 Oct 4 |
|
| The interplay of inverted redox potentials and aromaticity in the oxidized states of new pi-electron donors: 9-(1,3-dithiol-2-ylidene)fluorene and 9-(1,3-dithiol-2-ylidene)thioxanthene derivatives. | 2006 Apr 12 |
|
| Biochemical and pharmacological properties of an allosteric modulator site of the human P-glycoprotein (ABCB1). | 2006 Jul 14 |
|
| Remarkable interplay of redox states and conformational changes in a sterically crowded, cross-conjugated tetrathiafulvalene vinylog. | 2006 Jul 17 |
|
| Schisandrol A from Schisandra chinensis reverses P-glycoprotein-mediated multidrug resistance by affecting Pgp-substrate complexes. | 2007 Mar |
|
| Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998-2005. | 2007 Sep 25 |
|
| Application of chaotropic effect in reversed-phase liquid chromatography of structurally related phenothiazine and thioxanthene derivatives. | 2008 May 30 |
|
| Driving forces for the mutual conversions between phenothiazines and their various reaction intermediates in acetonitrile. | 2008 Sep 18 |
|
| Development and validation of an HPLC method for the rapid and simultaneous determination of 6-mercaptopurine and four of its metabolites in plasma and red blood cells. | 2009 Feb 20 |
|
| Spectroscopic and electrochemical analysis of psychotropic drugs. | 2009 Jan |
|
| Selective MMP-12 inhibitors: WO-2008057254. | 2009 Jul |
|
| Energetic studies and phase diagram of thioxanthene. | 2009 Nov 19 |
|
| Radiation resistance in glioma cells determined by DNA damage repair activity of Ape1/Ref-1. | 2010 |
|
| Research on antipsychotics in India. | 2010 Jan |
|
| Methotrimeprazine-induced corneal deposits and cataract revealed by urine drug profiling test. | 2010 Nov |
|
| Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects. | 2010 Sep |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 01:28:39 GMT 2023
by
admin
on
Sat Dec 16 01:28:39 GMT 2023
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| Record UNII |
1J3P67894A
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| Record Status |
Validated (UNII)
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| Record Version |
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| Code System | Code | Type | Description | ||
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205-972-1
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261-31-4
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51055
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Thioxanthene
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DTXSID20180732
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m10792
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67495
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51056
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C054700
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1J3P67894A
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admin on Sat Dec 16 01:28:39 GMT 2023 , Edited by admin on Sat Dec 16 01:28:39 GMT 2023
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