IPROCLOZIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.702
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)NNC(=O)COC1=CC=C(Cl)C=C1

InChI

InChIKey=GGECDTUJZOXAAR-UHFFFAOYSA-N

InChI=1S/C11H15ClN2O2/c1-8(2)13-14-11(15)7-16-10-5-3-9(12)4-6-10/h3-6,8,13H,7H2,1-2H3,(H,14,15)

HIDE SMILES / InChI

Molecular Formula	C11H15ClN2O2
Molecular Weight	242.702
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14145285 | https://www.ncbi.nlm.nih.gov/pubmed/5930723 | https://www.ncbi.nlm.nih.gov/pubmed/5879028 | https://www.ncbi.nlm.nih.gov/pubmed/6794533 | https://www.ncbi.nlm.nih.gov/pubmed/5526214 | https://www.ncbi.nlm.nih.gov/pubmed/680506

Iproclozide [1-(p-chlorophenoxyacetyl)-2-isopropylhydrazine] is a non-selective monoamine oxidase inhibitor. It has been used in the treatment of depressive states. Iproclozide was studied in the treatment of hypertension and angina pectoris. It may induce fatal hepatitis.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Monoamine oxidase 32 Target ID: CHEMBL2095205 Sources: https://www.ncbi.nlm.nih.gov/pubmed/680506	Inhibitor 8297

PubMed

Title	Date	PubMed
[Depressive states in a sanatorium milieu and monoamine oxidase inhibitors. (Therapeutic results by the combination of iproclozide and chlordiazepoxide). Apropos of 146 cases].	1966 Apr 5	5930723
Iproclozide fulminant hepatitis. Possible role of enzyme induction.	1978 Sep	680506

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:50:06 UTC 2023` Edited by `admin` on `Sat Dec 16 17:50:06 UTC 2023`
Record UNII	1II9D6CB3J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IPROCLOZIDE

Official Name

English

(P-CHLOROPHENOXY)ACETIC ACID 2-ISOPROPYLHYDRAZIDE

Common Name

English

PC-603

Code

English

iproclozide [INN]

Common Name

English

IPROCLOZIDE [MART.]

Common Name

English

Iproclozide [WHO-DD]

Common Name

English

IPROCLOZIDE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265