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Details

Stereochemistry MIXED
Molecular Formula C12H22N4S4
Molecular Weight 350.59
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MILNEB

SMILES

CC1NC(C)N(CCN2C(C)NC(C)SC2=S)C(=S)S1

InChI

InChIKey=JZFICWYCTCCINF-UHFFFAOYSA-N
InChI=1S/C12H22N4S4/c1-7-13-9(3)19-11(17)15(7)5-6-16-8(2)14-10(4)20-12(16)18/h7-10,13-14H,5-6H2,1-4H3

HIDE SMILES / InChI

Molecular Formula C12H22N4S4
Molecular Weight 350.59
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
[Benzimidazo-pyrimidino-imidazo-thiadiazines pharmacologically active].
2011-04-19
Polythia-zide.
2010-06-16
3-Chloro-N-(4-sulfamoylphen-yl)propanamide.
2010-06-05
Evaluation of a modified QuEChERS method for the extraction of pesticides from agricultural, ornamental and forestal soils.
2010-03
New fluorinated 1,2,4-benzothiadiazine 1,1-dioxides: discovery of an orally active cognitive enhancer acting through potentiation of the 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors.
2010-02-25
Evaluation of multi-walled carbon nanotubes as solid-phase extraction adsorbents of pesticides from agricultural, ornamental and forestal soils.
2009-08-11
Development of a novel virtual screening cascade protocol to identify potential trypanothione reductase inhibitors.
2009-03-26
New sulphonamide and carboxamide derivatives of acyclic C-nucleosides of triazolo-thiadiazole and the thiadiazine analogues. Synthesis, anti-HIV, and antitumor activities. Part 2.
2008-09
Identification of halosalicylamide derivatives as a novel class of allosteric inhibitors of HCV NS5B polymerase.
2008-06-01
In-vitro anti-HIV and antitumor activity of new 3,6-disubstituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles and thiadiazine analogues.
2008-06
Recent advances in antiviral activity of benzo/heterothiadiazine dioxide derivatives.
2008
The actions of a novel potent islet beta-cell specific ATP-sensitive K+ channel opener can be modulated by syntaxin-1A acting on sulfonylurea receptor 1.
2007-08
Emerging antifungal azoles and effects on Magnaporthe grisea.
2006-06
Thiourea, triazole and thiadiazine compounds and their metal complexes as antifungal agents.
2005-08
In vitro activities of thiadiazine derivatives against Leishmania amazonensis.
2005
Effect of thiadiazine derivatives on intracellular amastigotes of Leishmania amazonensis.
2004-05
Synthesis of pyrazole derivatives and their evaluation as photosynthetic electron transport inhibitors.
2004-04-07
Kinetic profile of a heterocyclic HCV replicon RNA synthesis inhibitor.
2003-11-21
Benzothiadiazine dioxide human cytomegalovirus inhibitors: synthesis and antiviral evaluation of main heterocycle modified derivatives.
2003-03
2-alkyl-3-Alkylamino-2H-Benzo- and pyridothiadiazine 1,1-dioxides: from K+ATP channel openers to Ca++ channel blockers?
2002-11
Structure-based design and synthesis of potent matrix metalloproteinase inhibitors derived from a 6H-1,3,4-thiadiazine scaffold.
2001-09-27
Novel heterocyclic inhibitors of matrix metalloproteinases: three 6H-1,3,4-thiadiazines.
2001-05
New thiadiazine derivatives with activity against Trypanosoma cruzi amastigotes.
2001
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:56:03 GMT 2025
Edited
by admin
on Mon Mar 31 21:56:03 GMT 2025
Record UNII
1GJG42DIN4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MILNEB
Common Name English
D-328
Preferred Name English
EDITONE
Brand Name English
3,3-ETHYLENEBIS(4,6-DIMETHYLTETRAHYDRO-1,3,5-THIADIAZINE-2-THIONE)
Common Name English
2H-1,3,5-THIADIAZINE-2-THIONE, 3,3'-ETHYLENEBIS(TETRAHYDRO-4,6-DIMETHYL-
Systematic Name English
THIADIAZIN
Systematic Name English
HOE-2852
Code English
2H-1,3,5-THIADIAZINE-2-THIONE, 3,3'-(1,2-ETHANEDIYL)BIS(TETRAHYDRO-4,6-DIMETHYL-
Systematic Name English
3,3'-ETHYLENEBIS(TETRAHYDRO-4,6-DIMETHYL-2H-1,3,5-THIADIAZINE-2-THIONE)
Systematic Name English
SANIPA
Brand Name English
EDITHON
Brand Name English
D-682
Brand Name English
EDITON
Brand Name English
2H-1,3,5-THIADIAZINE-2-THIONE, 3,3'-(1,2-ETHANEDIYL)BIS(3,4,5,6-TETRAHYDRO-4,6-DIMETHYL-
Systematic Name English
Code System Code Type Description
CAS
3773-49-7
Created by admin on Mon Mar 31 21:56:03 GMT 2025 , Edited by admin on Mon Mar 31 21:56:03 GMT 2025
PRIMARY
PUBCHEM
92200
Created by admin on Mon Mar 31 21:56:03 GMT 2025 , Edited by admin on Mon Mar 31 21:56:03 GMT 2025
PRIMARY
ALANWOOD
milneb
Created by admin on Mon Mar 31 21:56:03 GMT 2025 , Edited by admin on Mon Mar 31 21:56:03 GMT 2025
PRIMARY
FDA UNII
1GJG42DIN4
Created by admin on Mon Mar 31 21:56:03 GMT 2025 , Edited by admin on Mon Mar 31 21:56:03 GMT 2025
PRIMARY
EPA CompTox
DTXSID6042159
Created by admin on Mon Mar 31 21:56:03 GMT 2025 , Edited by admin on Mon Mar 31 21:56:03 GMT 2025
PRIMARY