Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H6Cl4 |
| Molecular Weight | 291.988 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC(=C(Cl)C=C1)C2=C(Cl)C=CC(Cl)=C2
InChI
InChIKey=HCWZEPKLWVAEOV-UHFFFAOYSA-N
InChI=1S/C12H6Cl4/c13-7-1-3-11(15)9(5-7)10-6-8(14)2-4-12(10)16/h1-6H
| Molecular Formula | C12H6Cl4 |
| Molecular Weight | 291.988 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Induction of aberrant mitosis with PCBs: particular efficiency of 2, 3,3',4,4'-pentachlorobiphenyl and synergism with triphenyltin. | 2000 Jan |
|
| Induction of apoptotic cell death by a p53-independent pathway in neuronal SK-N-MC cells after treatment with 2,2',5,5'-tetrachlorobiphenyl. | 2001 Aug 28 |
|
| No enhancement in bioconcentration of organic contaminants by low levels of DOM. | 2001 Jul |
|
| Dietary uptake kinetics of 2,2',5,5'-tetrachlorobiphenyl in rainbow trout. | 2001 Jul |
|
| Effects of 2,2',5,5'-tetrachlorobiphenyl and biphenyl on cell membranes of Ralstonia eutropha H850. | 2001 Jun 12 |
|
| A systematic gene expression screen of Caenorhabditis elegans cytochrome P450 genes reveals CYP35 as strongly xenobiotic inducible. | 2001 Nov 15 |
|
| The effect of 2,5,2',5'-tetrachlorobiphenyl on growth and death of the cyanobacterium Anabaena flos-aquae. | 2001 Oct |
|
| Multiple effects of 2,2',5,5'-tetrachlorobiphenyl on oxidative phosphorylation in rat liver mitochondria. | 2002 Feb |
|
| Spectral interactions of tetrachlorobiphenyls with hepatic microsomal cytochrome p450 enzymes. | 2003 Dec 15 |
|
| Antagonism of aryl hydrocarbon receptor-dependent induction of CYP1A1 and inhibition of IgM expression by di-ortho-substituted polychlorinated biphenyls. | 2003 Feb 15 |
|
| Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short- and long-term memory in 30-day-old Sprague-Dawley rats. | 2004 Oct 15 |
|
| Synthesis of chlorinated and non-chlorinated biphenyl-2,3- and 3,4-catechols and their [2H3]-isotopomers. | 2004 Sep 21 |
|
| Effects of 2,2',5,5'-tetrachlorobiphenyl (PCB52) on migration of chicken primordial germ cells. | 2005 |
|
| Thyroid hormones in pregnancy in relation to environmental exposure to organochlorine compounds and mercury. | 2005 Aug |
|
| CYP35: xenobiotically induced gene expression in the nematode Caenorhabditis elegans. | 2005 Jun 1 |
|
| Occurrence of pesticides, polychlorinated biphenyls (PCBs), and heavy metals in sediments from the Dniester River, Moldova. | 2005 Nov |
|
| Effects of PCB 52 and PCB 77 on cell viability, [Ca(2+)](i) levels and membrane fluidity in mouse thymocytes. | 2006 Jan 16 |
|
| Ontogenetic alterations in molecular and structural correlates of dendritic growth after developmental exposure to polychlorinated biphenyls. | 2007 Apr |
|
| Experimental verification of a model describing solid phase microextraction (SPME) of freely dissolved organic pollutants in sediment porewater. | 2008 Aug |
|
| Genotoxic effects of PCB 52 and PCB 77 on cultured human peripheral lymphocytes. | 2008 Jun 30 |
|
| Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells. | 2009 Dec 10 |
|
| In vivo biotransformation of 3,3',4,4'-tetrachlorobiphenyl by whole plants-poplars and switchgrass. | 2009 Oct 1 |
|
| Determination of organochlorine pesticide and polychlorinated biphenyl levels in adipose tissue of infertile men. | 2010 Mar |
|
| Polychlorinated biphenyls (PCB-153) and (PCB-77) absorption in human liver (HepG2) and kidney (HK2) cells in vitro: PCB levels and cell death. | 2010 Nov |
|
| The effect of olestra on the absorption, excretion and storage of 2,2',5,5' tetrachlorobiphenyl; 3,3',4,4' tetrachlorobiphenyl; and perfluorooctanoic acid. | 2010 Nov |
|
| Auditory effects of developmental exposure to purity-controlled polychlorinated biphenyls (PCB52 and PCB180) in rats. | 2011 Jul |
|
| Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs. | 2011 Oct 10 |
|
| Transcriptomics identifies differences between ultrapure non-dioxin-like polychlorinated biphenyls (PCBs) and dioxin-like PCB126 in cultured peripheral blood mononuclear cells. | 2011 Sep 5 |
|
| Neurodevelopmental and behavioral toxicity via lactational exposure to the sum of six indicator non-dioxin-like-polychlorinated biphenyls (∑6 NDL-PCBs) in mice. | 2012 Sep 4 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:58:35 GMT 2023
by
admin
on
Fri Dec 15 17:58:35 GMT 2023
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| Record UNII |
1EH557950R
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| Record Status |
Validated (UNII)
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| Record Version |
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35693-99-3
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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METABOLITE -> PARENT |
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