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Details

Stereochemistry RACEMIC
Molecular Formula C20H24N2O7
Molecular Weight 404.4145
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BAY-R-9425

SMILES

CC1=C(C(c2ccccc2N(=O)=O)C(=C(C)N1)C(=O)OCC(C)(C)O)C(=O)OC

InChI

InChIKey=MOZPKZYMNVFLSU-UHFFFAOYSA-N
InChI=1S/C20H24N2O7/c1-11-15(18(23)28-5)17(13-8-6-7-9-14(13)22(26)27)16(12(2)21-11)19(24)29-10-20(3,4)25/h6-9,17,21,25H,10H2,1-5H3

HIDE SMILES / InChI

Molecular Formula C20H24N2O7
Molecular Weight 404.4145
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Substance Class Chemical
Created
by admin
on Sat Jun 26 07:59:54 UTC 2021
Edited
by admin
on Sat Jun 26 07:59:54 UTC 2021
Record UNII
1E1602DWGD
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BAY-R-9425
Common Name English
3,5-PYRIDINEDICARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-4-(2-NITROPHENYL)-, 3-(2-HYDROXY-2-METHYLPROPYL) 5-METHYL ESTER
Systematic Name English
NISOLDIPINE (M9)
Common Name English
BAY-R 9425
Code English
Code System Code Type Description
CAS
106685-70-5
Created by admin on Sat Jun 26 07:59:54 UTC 2021 , Edited by admin on Sat Jun 26 07:59:54 UTC 2021
PRIMARY
PUBCHEM
184690
Created by admin on Sat Jun 26 07:59:54 UTC 2021 , Edited by admin on Sat Jun 26 07:59:54 UTC 2021
PRIMARY
FDA UNII
1E1602DWGD
Created by admin on Sat Jun 26 07:59:54 UTC 2021 , Edited by admin on Sat Jun 26 07:59:54 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> METABOLITE
Although M9 showed small pharmacological activity ? qualitatively similar to nisoldipine ? in animal models, it does not contribute significantly to the haemodynamic effects of the drug in humans.
PLASMA