OXYPYRRONIUM BROMIDE

Details

Stereochemistry	MIXED
Molecular Formula	C21H32NO3.Br
Molecular Weight	426.388
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Br-].C[N+]1(C)CCCC1COC(=O)C(O)(C2CCCCC2)C3=CC=CC=C3

InChI

InChIKey=SXGOKQARVJHRML-UHFFFAOYSA-M

InChI=1S/C21H32NO3.BrH/c1-22(2)15-9-14-19(22)16-25-20(23)21(24,17-10-5-3-6-11-17)18-12-7-4-8-13-18;/h3,5-6,10-11,18-19,24H,4,7-9,12-16H2,1-2H3;1H/q+1;/p-1

HIDE SMILES / InChI

Molecular Formula	C21H31NO3
Molecular Weight	345.4757
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA926&lpg=PA926&dq=IMMETROPAN&source=bl&ots=6JTjo1RApw&sig=ACfU3U1ygccwCtqa4b6GFoDucx2-7rnQCA&hl=en&sa=X&ved=2ahUKEwisufG72cvhAhXtw8QBHbLJACMQ6AEwC3oECBYQAQ#v=onepage&q=IMMETROPAN&f=false | https://www.jstage.jst.go.jp/article/fpj1944/66/6/66_6_607/_pdf/-char/ja | https://www.ncbi.nlm.nih.gov/pubmed/14157072

Oxypyrronium is an anticholinergic and spasmolytic agent containing quaternary ammonium. In animal models it inhibited gastric motility, hypotension induced by vagus stimulation or intravenation of acetylcholine; salivation induced by chorda tympani nerve stimulation, and contraction elicited by preganglionic cervical sympathetic nerve stimulation. Oxypyrronium was marketed in France under tradename Immetropan for the treatment of gastric pain.

Approval Year

PubMed

Title	Date	PubMed
[Clinical study of a new drug for gastric pain: L.D. 3055].	1962-11	13930250

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:17:04 GMT 2025` Edited by `admin` on `Mon Mar 31 18:17:04 GMT 2025`
Record UNII	1D79RM7Q04
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IMETRO

Preferred Name

English

OXYPYRRONIUM BROMIDE

Official Name

English

2-(2-HYDROXYMETHYL)-1,1-DIMETHYL)PYRROLIDINIUM BROMIDE .ALPHA.-PHENYLCYCLOHEXANEGLYCOLATE

Common Name

English

BRL-556

Code

English

PYRROLIDINIUM, 2-(((2-CYCLOHEXYL-2-HYDROXY-2-PHENYLACETYL)OXY)METHYL)-1,1-DIMETHYL-, BROMIDE (1:1)

Systematic Name

English

IMMETROPAN

Brand Name

English

LD 3055

Code

English

LD-3055

Code

English

oxypyrronium bromide [INN]

Common Name

English

BM-3055

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C66880