CHLORMERODRIN HG-197

US Previously Marketed

First approved in 1974

Details

Stereochemistry	RACEMIC
Molecular Formula	C5H11HgN2O2.Cl
Molecular Weight	363.573
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Cl-].COC(C[197Hg+])CNC(N)=O

InChI

InChIKey=BJFGVYCULWBXKF-WUYZZQIKSA-M

InChI=1S/C5H11N2O2.ClH.Hg/c1-4(9-2)3-7-5(6)8;;/h4H,1,3H2,2H3,(H3,6,7,8);1H;/q;;+1/p-1/i;;1-4

HIDE SMILES / InChI

Molecular Formula	C5H11HgN2O2
Molecular Weight	328.1202
Charge	1
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/68002717 | http://www.hmdb.ca/metabolites/HMDB0014674

CHLORMERODRIN HG-197 is a radiolabelled form of chlormerodrin, an organomercury compound that was previously used as a diuretic. Its radiolabelled form was used as diagnostics in brain scans.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
intraocular tumours 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4647129	Diagnostic		Approved 8429	HLORMERODRIN HG 197 Approved Use Unknown

PubMed

Title	Date	PubMed
BRAIN SCANS IN DIAGNOSIS OF BRAIN TUMORS: SCANNING WITH CHLORMERODRIN HG 203 AND CHLORMERODRIN HG 197.	1965 Feb 8	14242415
BRAIN SCANS IN NONNEOPLASTIC INTRACRANIAL LESIONS: SCANNING WITH CHLORMERODRIN HG 203 AND CHLORMERODRIN HG 197.	1965 Feb 8	14238022
BRAIN SCANS IN NEOPLASTIC INTRACRANIAL LESIONS: SCANNING WITH CHLORMERODRIN HG 203 AND CHLORMERODRIN HG 197.	1965 May 31	14289436

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:05:56 GMT 2023` Edited by `admin` on `Fri Dec 15 15:05:56 GMT 2023`
Record UNII	1D6EFC579A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CHLORMERODRIN HG-197

Common Name

English

CHLORMERODRIN HG-197 [ORANGE BOOK]

Common Name

English

chlormerodrin (¹⁹⁷Hg) [INN]

Common Name

English

CHLORMERODRIN (197HG)

Official Name

English

MERCURY(SUP 197) HG,(3-((AMINOCARBONYL)AMINO)-2-METHOXYPROPYL)CHLORO-

Common Name

English

CHLORMERODRIN, HG-197

Common Name

English

CHLORMERODRIN HG 197

Official Name

English

CHLORO(2-METHOXY-3-UREIDOPROPYL)MERCURY-(SUP 197)HG

Common Name

English

CHLORMERODRIN (197 HG)

Common Name

English

CHLORMERODRIN HG 197 [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1937