CLIVATUZUMAB TETRAXETAN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:50:44 GMT 2025` Edited by `admin` on `Mon Mar 31 21:50:44 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	1D1F7UG35J
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

HPAM-4

Preferred Name

English

CLIVATUZUMAB TETRAXETAN

Official Name

English

clivatuzumab tetraxetan [INN]

Common Name

English

HPAM4

Code

English

IMMUNOGLOBULIN G1, ANTI-(MUCIN) (HUMAN-MUS MUSCULUS MONOCLONAL HPAM4 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL HPAM4 .KAPPA.-CHAIN, DIMER, 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID CONJUGATE

Common Name

English

CLIVATUZUMAB TETRAXETAN [USAN]

Common Name

English

IGG-DOTA

Code

English

Code System Code Type Description

INN

10103

Created by admin on Mon Mar 31 21:50:44 GMT 2025 , Edited by admin on Mon Mar 31 21:50:44 GMT 2025

PRIMARY

NCI_THESAURUS

C166491

Created by admin on Mon Mar 31 21:50:44 GMT 2025 , Edited by admin on Mon Mar 31 21:50:44 GMT 2025

PRIMARY

EVMPD

SUB177948

Created by admin on Mon Mar 31 21:50:44 GMT 2025 , Edited by admin on Mon Mar 31 21:50:44 GMT 2025

PRIMARY

ChEMBL

CHEMBL3301586

Created by admin on Mon Mar 31 21:50:44 GMT 2025 , Edited by admin on Mon Mar 31 21:50:44 GMT 2025

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FDA UNII

1D1F7UG35J

Created by admin on Mon Mar 31 21:50:44 GMT 2025 , Edited by admin on Mon Mar 31 21:50:44 GMT 2025

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USAN

BC-60

Created by admin on Mon Mar 31 21:50:44 GMT 2025 , Edited by admin on Mon Mar 31 21:50:44 GMT 2025

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CAS

1462876-11-4

Created by admin on Mon Mar 31 21:50:44 GMT 2025 , Edited by admin on Mon Mar 31 21:50:44 GMT 2025

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SMS_ID

100000163597

Created by admin on Mon Mar 31 21:50:44 GMT 2025 , Edited by admin on Mon Mar 31 21:50:44 GMT 2025

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From	To
1_22	1_96
1_146	1_202
1_222	3_215
1_228	2_228
1_231	2_231
1_263	1_323
1_369	1_427
2_22	2_96
2_146	2_202
2_222	4_215
2_263	2_323
2_369	2_427
3_23	3_89
3_135	3_195
4_23	4_89
4_135	4_195

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					1HTE449DGZ

DERIVATIVE -> PARENT

Amount:


					RGU8A332UL

CONJUGATE COMPONENT->CONJUGATE

Amount:


					I903D7RK7W

MUCIN-1

TARGET->LIGAND

Amount:

Related Record Type Details


					1D1F7UG35J

CLIVATUZUMAB TETRAXETAN

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION		RESIDUE_SPECIFIC	K	Amount:	LYSINE-DOTA	KTZ0L57AI1

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL