U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Cl.Sn.2H2O
Molecular Weight 225.647
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of STANNOUS CHLORIDE

SMILES

O.O.[Cl-].[Cl-].[SnH2++]

InChI

InChIKey=GATSHYKZJFLTJA-UHFFFAOYSA-L
InChI=1S/2ClH.2H2O.Sn.2H/h2*1H;2*1H2;;;/q;;;;+2;;/p-2

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Sn
Molecular Weight 118.71
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including: https://www.ncbi.nlm.nih.gov/pubmed/17645550 http://www.pharmacytimes.com/publications/issue/2014/august2014/r648_august2014 https://en.wikipedia.org/wiki/Tin(II)_fluoride

Readily soluble in water, SnF2 is hydrolysed. At low concentration, it forms species such as SnOH+, Sn(OH)2 and Sn(OH)3−. At higher concentrations, predominantly polynuclear species are formed, including Sn2(OH)22+ and Sn3(OH)42+. Aqueous solutions readily oxidise to form insoluble precipitates of SnIV, which are ineffective as a dental prophylactic. Tin(II) fluoride, commonly referred to commercially (with tin(II) in Latin) as stannous fluoride, is a chemical compound with the formula SnF2. It is a colorless solid used as an ingredient in toothpastes that are typically more expensive than those that use sodium fluoride. Stannous fluoride has both bactericidal and bacteriostatic properties, which fight plaque and treat/prevent gingivitis. The stannous fluoride also deposits a protective mineral barrier over exposed dentinal tubules to help prevent sensitivity pain from triggers such as hot or cold liquids and foods. Stannous fluoride is used under the trade name "Fluoristan" in the original formulation of the toothpaste Crest, though it was later replaced with sodium monofluorophosphate, or "Fluoristat". It is the active ingredient in Crest Pro Health brand toothpaste. Crest Pro Health issues a warning on the tube that stannous fluoride may cause staining, which can be avoided by proper brushing, and that its particular formulation is resistant to staining. Any stannous fluoride staining that occurs due to improper brushing is not permanent. Stannous fluoride is also used in Oral-B Pro-Expert. Stannous fluoride is also readily available in over-the-counter rinses.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
ULTRATAG RBC

Approved Use

Technetium Tc 99m-labeled red blood cells are used for blood pool imaging, including cardiac first pass and gated equilibrium imaging and for detection of sites of gastrointestinal bleeding.
Preventing
Unknown

Approved Use

Unknown
Preventing
Unknown

Approved Use

Unknown
Preventing
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Effects of trace metal compounds on HIV-1 reverse transcriptase: an in vitro study.
1999 May
Patents

Patents

Sample Use Guides

Unknown
Route of Administration: Dental
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:43:09 GMT 2023
Edited
by admin
on Fri Dec 15 15:43:09 GMT 2023
Record UNII
1BQV3749L5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
STANNOUS CHLORIDE
FCC   II   INCI   USAN   VANDF  
INCI   USAN  
Official Name English
TIN(II) CHLORIDE DIHYDRATE
Systematic Name English
TIN CHLORIDE (SNCL2)DIHYDRATE
Common Name English
TIN, DICHLORO-, HYDRATE (1:2)
Systematic Name English
INS NO.512
Code English
STANNOUS CHLORIDE [INCI]
Common Name English
STANNOUS CHLORIDE, DIHYDRATE
Common Name English
E-512
Code English
STANNOUS CHLORIDE [USAN]
Common Name English
STANNOUS CHLORIDE DIHYDRATE
EP   MI   WHO-DD  
Common Name English
STANNOUS CHLORIDE [FCC]
Common Name English
TIN (II) CHLORIDE
Systematic Name English
STANNOUS CHLORIDE [VANDF]
Common Name English
INS-512
Code English
STANNOUS CHLORIDE [II]
Common Name English
STANNOUS CHLORIDE DIHYDRATE [MI]
Common Name English
TIN CHLORIDE DIHYDRATE
Systematic Name English
Stannous chloride dihydrate [WHO-DD]
Common Name English
STANNOUS CHLORIDE DIHYDRATE [EP MONOGRAPH]
Common Name English
STANNOUS CHLORIDE DIHYDRATE [EP IMPURITY]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 172.180
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
JECFA EVALUATION INS-512
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
CODEX ALIMENTARIUS (GSFA) INS-512
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
CFR 21 CFR 184.1845
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C74343
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
ECHA (EC/EINECS)
215-689-5
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
CAS
10025-69-1
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
MERCK INDEX
m10180
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY Merck Index
DAILYMED
1BQV3749L5
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
CAS
1344-13-4
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
NON-SPECIFIC STOICHIOMETRY
FDA UNII
1BQV3749L5
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
CHEBI
78074
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
CONCEPT Industrial Aid
EVMPD
SUB15373MIG
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PRIMARY
RXCUI
37032
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY RxNorm
WIKIPEDIA
Stannous chloride
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
PUBCHEM
142989328
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
EVMPD
SUB12595MIG
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
EPA CompTox
DTXSID5049788
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
DRUG BANK
DB11056
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
MESH
C023599
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
SMS_ID
100000090531
Created by admin on Fri Dec 15 15:43:10 GMT 2023 , Edited by admin on Fri Dec 15 15:43:10 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
ANHYDROUS->SOLVATE
Related Record Type Details
ACTIVE MOIETY