RO-41-1049 HYDROCHLORIDE

Cl.NCCNC(=O)C1=C(SC=N1)C2=CC(F)=CC=C2

InChIKey=RRNSPXUFTKJIEZ-UHFFFAOYSA-N

InChI=1S/C12H12FN3OS.ClH/c13-9-3-1-2-8(6-9)11-10(16-7-18-11)12(17)15-5-4-14;/h1-3,6-7H,4-5,14H2,(H,15,17);1H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Increased density of catalytic sites and expression of brain monoamine oxidase A in humans with hepatic encephalopathy.	1997 Mar	9048767
Differential substrate specificity of monoamine oxidase in the rat heart and renal cortex.	2003 Jul 11	12818349
MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway.	2007 Jul 1	17561096
Up-regulation of the isoenzymes MAO-A and MAO-B in the human basal ganglia and pons in Huntington's disease revealed by quantitative enzyme radioautography.	2011 Jan 25	21075085

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:55:18 GMT 2023` Edited by `admin` on `Sat Dec 16 10:55:18 GMT 2023`
Record UNII	19Z49HUF4G
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

RO-41-1049 HYDROCHLORIDE

Common Name

English

4-THIAZOLECARBOXAMIDE, N-(2-AMINOETHYL)-5-(3-FLUOROPHENYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

CAS

127917-66-2

Created by admin on Sat Dec 16 10:55:18 GMT 2023 , Edited by admin on Sat Dec 16 10:55:18 GMT 2023

PRIMARY

FDA UNII

19Z49HUF4G

Created by admin on Sat Dec 16 10:55:18 GMT 2023 , Edited by admin on Sat Dec 16 10:55:18 GMT 2023

PRIMARY

PUBCHEM

5311308

Created by admin on Sat Dec 16 10:55:18 GMT 2023 , Edited by admin on Sat Dec 16 10:55:18 GMT 2023

PRIMARY

Related Record Type Details


					40Y4916ZJ4

ACTIVE MOIETY