MAGNESIUM BICARBONATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2CHO3.Mg
Molecular Weight	146.3387
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Mg++].OC([O-])=O.OC([O-])=O

InChI

InChIKey=QWDJLDTYWNBUKE-UHFFFAOYSA-L

InChI=1S/2CH2O3.Mg/c2*2-1(3)4;/h2*(H2,2,3,4);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula	CH2O3
Molecular Weight	62.0248
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Mg
Molecular Weight	24.305
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8770963http://www.dancingwithwater.com/articles/magnesium-bicarbonate-water-the-importance-of-bicarbonates-and-magnesium/
Curator's Comment: description was created based on several sources, including: https://www.ncbi.nlm.nih.gov/pubmed/24754016 / http://www.uniquewater.com.au/

Magnesium bicarbonate supplemented water provides a source of orally available magnesium. A one-month intake of mineral water rich in calcium, magnesium bicarbonate, and sulfate decreased cholesterol and LDL levels but not TG or HDL levels in dyslipidemic adults. Optimal hydration with Unique Water (Magnesium bicarbonate liquid) over three months may significantly increase blood magnesium levels, may significantly stabilise blood parathyroid hormone levels and may significantly increase blood albumin protein levels.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
magnesium ion homeostasis 70 Target ID: GO:0010960 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9070556	Modulator 828
Magnesium-bicarbonate ATPase 2 Target ID: Magnesium-bicarbonate ATPase Sources: https://www.ncbi.nlm.nih.gov/pubmed/162573	Activator 1430

Conditions

Condition	Modality	Highest Phase	Product
Mitral valve prolapse syndrome 2 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9070556	Palliative	Phase II 1132	Unknown Approved Use Unknown
Paroxysmal supraventricular tachycardia 7 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7483616	Preventing	Phase II 1132	Unknown Approved Use Unknown
Hyperphosphatemia 30 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21812357	Primary	Phase II 1132	Unknown Approved Use Unknown
Dyslipidemia 30 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20579398	Primary	Not Provided 504	Unique Water Approved Use Unknown

PubMed

Title	Date	PubMed
[Magnesium or proajmaline (neogilurytmal) in treatment of recurrences of paroxysmal supraventricular tachyarrhythmias?].	1994 Oct	7483616
Clinical symptoms of mitral valve prolapse are related to hypomagnesemia and attenuated by magnesium supplementation.	1997 Mar 15	9070556
A double-blind, placebo-controlled study of the short term effects of a spring water supplemented with magnesium bicarbonate on acid/base balance, bone metabolism and cardiovascular risk factors in postmenopausal women.	2010 Jun 28	20579398
[The influence of short-term magnesium carbonate treatment on calcium-phosphorus balance in dialysis patients].	2011	21812357
[Clinical aspects of antimicrobial therapy used in patients with urogenital infections].	2012	23479999
Hypolipidemic activity of a natural mineral water rich in calcium, magnesium, and bicarbonate in hyperlipidemic adults.	2014	24754016

Patents

Sample Use Guides

In Vivo Use Guide

3 x 0.6 mg during 3 months

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:13:27 GMT 2023` Edited by `admin` on `Fri Dec 15 19:13:27 GMT 2023`
Record UNII	19E9A0647O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MAGNESIUM BICARBONATE

Systematic Name

English

KRUSE'S FLUID MAGNESIA

Brand Name

English

MAGNESIUM HYDROCARBONATE

Common Name

English

Magnesium bicarbonate [WHO-DD]

Common Name

English

Code System Code Type Description

PUBCHEM

102204