U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C4H12O4Si
Molecular Weight 152.2212
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TETRAMETHYL SILICATE

SMILES

CO[Si](OC)(OC)OC

InChI

InChIKey=LFQCEHFDDXELDD-UHFFFAOYSA-N
InChI=1S/C4H12O4Si/c1-5-9(6-2,7-3)8-4/h1-4H3

HIDE SMILES / InChI

Molecular Formula C4H12O4Si
Molecular Weight 152.2212
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Mechanism of the catalytic activity of nucleophiles in the stepwise hydrolysis and condensation reactions of tetramethoxysilane.
2009-04-14
An overview of silica in biology: its chemistry and recent technological advances.
2009
Preparation of primary amine-based block copolymer vesicles by direct dissolution in water and subsequent stabilization by sol-gel chemistry.
2008-12-02
UV and thermally stable superhydrophobic coatings from sol-gel processing.
2008-10-15
Rapid micropatterning of mesoporous silica film by site-selective low-energy electron beam irradiation.
2008-10-07
[Study on the fluorescence characteristics of BOD sensing films immobilizing different limnetic microorganism].
2008-09
Synthesis and applications of crack-free SiO2 monolith containing CdSe/ZnS quantum dots as passive lighting sources.
2008-09
Structure and performance of silica-based monolithic HPLC columns.
2008-08
Anion exchange silica monolith for capillary liquid chromatography.
2008-08
Sol-gel synthesis of low-dimensional silica within coordination nanochannels.
2008-07-23
Biosilicification of dual-fusion enzyme immobilized on magnetic nanoparticle.
2008-06-01
Single-step approach to beta-cyclodextrin-bonded silica as monolithic stationary phases for CEC.
2008-06
Favourable influence of hydrophobic surfaces on protein structure in porous organically-modified silica glasses.
2008-06
Direct synthesis of hierarchical monolithic silica for high performance liquid chromatography.
2008-05-09
Core-shell nanoparticles: characterization and study of their use for the encapsulation of hydrophobic fluorescent dyes.
2008-03-04
Particle morphology of various SiC-based nanocomposite powders made by the aerosol-assisted synthesis method.
2008-02
Calix[4] open-chain crown ether-modified, vinyl-functionalized hybrid silica monolith for capillary electrochromatography.
2008-02
Simultaneous analysis of basic, acidic and neutral compounds on an endcapped octadecylsilane silica-based monolith by pressure-assisted capillary electrochromatography.
2008-02
Sila-haloperidol, a silicon analogue of the dopamine (D2) receptor antagonist haloperidol: synthesis, pharmacological properties, and metabolic fate.
2008-01
Luminescent amino-functionalized or erbium-doped silica spheres for biological applications.
2008
Preparation of a high pH-resistant AAPTS-silica coating and its application to capillary microextraction (CME) of Cu, Zn, Ni, Hg and Cd from biological samples followed by on-line ICP-MS detection.
2007-12-12
The effect of pH on coupled mass transfer and sol-gel reaction in a two-phase system.
2007-11-01
Development of a silica monolith microbioreactor entrapping highly activated lipase and an experiment toward integration with chromatographic separation of chiral esters.
2007-11
Zinc complexes of the biomimetic N,N,O ligand family of substituted 3,3-bis(1-alkylimidazol-2-yl)propionates: the formation of oxalate from pyruvate.
2007-11
Biomimetic deposition of silica templated by a cationic polyamine-containing microgel.
2007-09-11
Preparation of high efficiency and highly retentive monolithic silica capillary columns for reversed-phase chromatography by chemical modification by polymerization of octadecyl methacrylate.
2007-07-13
Tris(2,2'-bipyridyl)ruthenium(II) electrochemiluminescence sensor based on carbon nanotube/organically modified silicate films.
2007-07-02
High-throughput determination of biochemical oxygen demand (BOD) by a microplate-based biosensor.
2007-06-01
Entrapment of fluorescence signaling DNA enzymes in sol-gel-derived materials for metal ion sensing.
2007-05-01
Synthesis of nitric oxide-releasing silica nanoparticles.
2007-04-18
Formation of silica nanoparticles in microemulsions.
2007-03-13
Fluorescent sensing layer for the determination of L-malic acid in wine.
2007-03
Electrochemical regeneration of NADH using conductive vanadia-silica xerogels.
2007-02-03
Electrochemiluminescence determination of codeine or morphine with an organically modified silicate film immobilizing Ru(bpy)3(2+).
2007-01-31
Quantum dot-doped silica nanoparticles as probes for targeting of T-lymphocytes.
2007
Preparation of novel silica-coated alginate gel beads for efficient encapsulation of yeast alcohol dehydrogenase.
2007
Study of the effects of progressive changes in alkoxysilane structure on sol-gel reactivity.
2006-11-16
Performance of monolithic silica capillary columns with increased phase ratios and small-sized domains.
2006-11-15
Influence of reaction parameters on size and shape of silica nanoparticles.
2006-11
Controlled production of ZnO nanoparticles from zinc glycerolate in a sol-gel silica matrix.
2006-10-01
Menger sponge-like fractal body created by a novel template method.
2006-09-28
A comparative study of immobilization techniques for urease on glass-pH-electrode and its application in urea detection in blood serum.
2006-09-25
Mechanisms of amine-catalyzed organosilicate hydrolysis at circum-neutral pH.
2006-09-14
[Study of the fluorescent response for optical ammonia sensing film].
2006-09
O(2)-responsive chemical sensors based on hybrid xerogels that contain fluorinated precursors.
2006-09
Towards biocompatibility of RE2O3 nanocrystals - water and organic molecules chemisorbed on Gd2O3 and Y2O3 nanocrystals studied by quantum-chemical computations.
2006-09
Microchip-based macroporous silica sol-gel monolith for efficient isolation of DNA from clinical samples.
2006-08-15
Encapsulation of biomolecules for bioanalytical purposes: preparation of diclofenac antibody-doped nanometer-sized silica particles by reverse micelle and sol-gel processing.
2006-07-28
[Research of Hg2+ sol-gel membrane made of organically modified silicates].
2006-07
Microstructures and structural properties of sol-gel silica foams.
2005-12-08
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:30:18 GMT 2025
Edited
by admin
on Mon Mar 31 21:30:18 GMT 2025
Record UNII
19D35VPL66
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TETRAMETHYL SILICATE
HSDB  
Systematic Name English
NSC-67383
Preferred Name English
TETRAMETHYL ESTER SILICATE
Common Name English
SILICIC ACID, TETRAMETHYL ESTER
Common Name English
METHYL ORTHOSILICATE
Systematic Name English
TETRAMETHOXYSILANE
Systematic Name English
TETRAMETHYL SILICATE [HSDB]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID3027291
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY
SMS_ID
300000053686
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY
WIKIPEDIA
Tetramethyl silicate
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY
MESH
C061205
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY
NSC
67383
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY
FDA UNII
19D35VPL66
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY
PUBCHEM
12682
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY
CAS
681-84-5
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY
HSDB
5511
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY
ECHA (EC/EINECS)
211-656-4
Created by admin on Mon Mar 31 21:30:18 GMT 2025 , Edited by admin on Mon Mar 31 21:30:18 GMT 2025
PRIMARY