SUVECALTAMIDE HYDROCHLORIDE

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H23F3N2O2.ClH
Molecular Weight	416.865
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SUVECALTAMIDE HYDROCHLORIDE

Structure Search

SMILES

Cl.CC(C)C1=CC=C(CC(=O)N[C@H](C)C2=NC=C(OCC(F)(F)F)C=C2)C=C1

InChI

InChIKey=KGFZANSMUKVDNC-PFEQFJNWSA-N

InChI=1S/C20H23F3N2O2.ClH/c1-13(2)16-6-4-15(5-7-16)10-19(26)25-14(3)18-9-8-17(11-24-18)27-12-20(21,22)23;/h4-9,11,13-14H,10,12H2,1-3H3,(H,25,26);1H/t14-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C20H23F3N2O2
Molecular Weight	380.404
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Potency
Voltage-gated T-type calcium channel alpha-1G subunit 8 Target ID: CHEMBL4641 Sources: https://adisinsight.springer.com/drugs/800048744\|https://www.ncbi.nlm.nih.gov/pubmed/29070417\|https://www.ncbi.nlm.nih.gov/pubmed/27933950	Antagonist 2849	1.2 nM [IC50]
Voltage-gated T-type calcium channel alpha-1I subunit 4 Target ID: CHEMBL5558 Sources: https://adisinsight.springer.com/drugs/800048744\|https://www.ncbi.nlm.nih.gov/pubmed/29070417\|https://www.ncbi.nlm.nih.gov/pubmed/27933950	Antagonist 2849	1.5 nM [IC50]
Voltage-gated T-type calcium channel alpha-1H subunit 7 Target ID: CHEMBL1859 Sources: https://adisinsight.springer.com/drugs/800048744\|https://www.ncbi.nlm.nih.gov/pubmed/29070417\|https://www.ncbi.nlm.nih.gov/pubmed/27933950	Antagonist 2849	8.2 nM [IC50]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:28:09 GMT 2025` Edited by `admin` on `Mon Mar 31 22:28:09 GMT 2025`
Record UNII	194ZA622JG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CX-8998 HYDROCHLORIDE

Preferred Name

English

SUVECALTAMIDE HYDROCHLORIDE

Official Name

English

JZP-385 HYDROCHLORIDE

Code

English

JZP385 HYDROCHLORIDE

Code

English

MK-8998 HYDROCHLORIDE

Code

English

SUVECALTAMIDE HYDROCHLORIDE [USAN]

Common Name

English

BENZENEACETAMIDE, 4-(1-METHYLETHYL)-N-((1R)-1-(5-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)ETHYL)-, HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

NCI_THESAURUS

C180663