2-NITROFLUORENE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H9NO2
Molecular Weight	211.2161
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O-][N+](=O)C1=CC=C2C(CC3=C2C=CC=C3)=C1

InChI

InChIKey=XFOHWECQTFIEIX-UHFFFAOYSA-N

InChI=1S/C13H9NO2/c15-14(16)11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7H2

HIDE SMILES / InChI

Molecular Formula	C13H9NO2
Molecular Weight	211.2161
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The preparation of anthraquinone used in the National Toxicology Program cancer bioassay was contaminated with the mutagen 9-nitroanthracene.	2001 Mar	11230561
Metabolism of 2-nitrofluorene, an environmental pollutant, and 2-acetylaminofluorene in fish.	2001 Mar	11178653
Metabolism of 2-nitrofluorene, an environmental pollutant, by liver preparations of sea bream, Pagrus major.	2002 Aug	12296988
Estrogenic activity of an environmental pollutant, 2-nitrofluorene, after metabolic activation by rat liver microsomes.	2003 Apr 4	12659833
Evaluation of the mutagenic, antimutagenic and antiproliferative potential of Croton lechleri (Muell. Arg.) latex.	2003 Mar	12725567
Antimutagenic activity of extracts of natural substances in the Salmonella/microsome assay.	2003 Mar	12621065
Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin.	2005 Sep	15932950
The antimutagenic activity of Lavandula angustifolia (lavender) essential oil in the bacterial reverse mutation assay.	2005 Sep	15907354
In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions.	2006 Nov	17132218
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
Surface-enhanced vibrational spectra of 2-nitrofluorene.	2007 Feb	16859958
Solvent and pH effects on the fluorescence of 7-(dimethylamino)-2-fluorenesulfonate.	2007 Jul	17522966
Polycyclic aromatic hydrocarbons (PAHs), nitrated PAHs and oxygenated PAHs in ambient air of the Marseilles area (South of France): concentrations and sources.	2007 Oct 1	17590415
Nitropolycyclic aromatic hydrocarbons are inducers of mitotic homologous recombination in the wing-spot test of Drosophila melanogaster.	2008 Jul	18440115
Oxidative transformation of 2-acetylaminofluorene by a chemical model for cytochrome P450: A water-insoluble porphyrin and tert-butyl hydroperoxide.	2008 Jul 15	18586499
Vapor pressures and thermodynamics of oxygen-containing polycyclic aromatic hydrocarbons measured using Knudsen effusion.	2008 Jun	18220445
Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole.	2009	20981287
Antimutagenic activity of a secoisopimarane diterpenoid from Salvia cinnabarina M. Martens et Galeotti in the bacterial reverse mutation assay.	2009 Aug	19497346
Mutagenicity of an aged gasworks soil during bioslurry treatment.	2009 Jun	19274766
Novel 7-(dimethylamino)fluorene-based fluorescent probes and their binding to human serum albumin.	2009 Oct 21	19795061
Pharmacological and phytochemical study on a Sisymbrium officinale Scop. extract.	2010 Feb 17	19969059
Antioxidant, anti-microbial and antimutagenicity activities of pistachio (Pistachia vera) green hull extract.	2010 Jan	19781589
Genotoxic and antimutagenic activities of extracts from pseudocereals in the Salmonella mutagenicity assay.	2010 Jun	20303377
Voltammetric detection of damage to DNA caused by nitro derivatives of fluorene using an electrochemical DNA biosensor.	2010 May	20186538
Correlation of the genotoxic activation and kinetic properties of Salmonella enterica serovar Typhimurium nitroreductases SnrA and cnr with the redox potentials of nitroaromatic compounds and quinones.	2010 May	20118186
A novel approach for a toxicity prediction model of environmental pollutants by using a quantitative structure-activity relationship method based on toxicogenomics.	2011	23724284
Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity.	2011 Dec	21873647
Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.	2012 Nov	23052194

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:13:41 GMT 2023` Edited by `admin` on `Fri Dec 15 19:13:41 GMT 2023`
Record UNII	191LL4U4GZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-NITROFLUORENE

Systematic Name

English

2-NITROFLUORENE [IARC]

Common Name

English

NITROFLUORENE, 2-

Systematic Name

English

NSC-5182

Code

English

2-NITRO-9H-FLUORENE [HSDB]

Common Name

English

Code System Code Type Description

MESH

C019499