TRIMYRISTIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C45H86O6
Molecular Weight	723.1607
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC

InChI

InChIKey=DUXYWXYOBMKGIN-UHFFFAOYSA-N

InChI=1S/C45H86O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-43(46)49-40-42(51-45(48)39-36-33-30-27-24-21-18-15-12-9-6-3)41-50-44(47)38-35-32-29-26-23-20-17-14-11-8-5-2/h42H,4-41H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C45H86O6
Molecular Weight	723.1607
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.hmdb.ca/metabolites/HMDB0042061 | https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=6aa6ad3f-2c52-4031-9e6c-7526c42de71d&type=display

TRIMYRISTIN is an inactive component of RODAN AND FIELDS ENHANCEMENTS used to prevent sunburns. TRIMYRISTIN is a constituent of nutmegs.

Approval Year

PubMed

Title	Date	PubMed
Anxiogenic activity of Myristica fragrans seeds.	2002 Jan-Feb	11812528
Monolithic glyceryl trimyristate matrices for parenteral drug release applications.	2003 Jan	12551714
A supercritical fluid-based coating technology. 2: solubility considerations.	2003 Jan-Feb	12519705
Cytotoxicity studies of Dynasan 114 solid lipid nanoparticles (SLN) on RAW 264.7 macrophages-impact of phagocytosis on viability and cytokine production.	2004 Jul	15233867
Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles.	2004 Mar 24	15023472
Dialkylphosphatidylcholine and egg yolk lecithin for emulsification of various triglycerides.	2005 Apr 10	15748826
Isostatic ultra-high-pressure effects on supercooled melts in colloidal triglyceride dispersions.	2005 Oct	16180129
Antibacterial principles from Myristica fragrans seeds.	2006 Fall	17004905
Pharmacokinetics, tissue distribution and bioavailability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration.	2006 Nov	17090399
Cloning, expression, and characterization of a cold-adapted lipase gene from an antarctic deep-sea psychrotrophic bacterium, Psychrobacter sp 7195.	2007 Apr	18051271
Preparation, characterization and in vitro cytotoxicity of paclitaxel-loaded sterically stabilized solid lipid nanoparticles.	2007 Apr	17257668
Mobility of Thermomyces lanuginosus lipase on a trimyristin substrate surface.	2007 Feb 27	17261037
Confocal microscopy for the elucidation of mass transport mechanisms involved in protein release from lipid-based matrices.	2007 Jul	17457662
Dynamics of different-sized solid-state nanocrystals as tracers for a drug-delivery system in the interstitium of a human tumor xenograft.	2009	19575785
Short chain saturated fatty acids decrease circulating cholesterol and increase tissue PUFA content in the rat.	2010 Nov	20924709
Composition and metabolism of carbohydrates and lipids in Sparus aurata semen and its relation to viability expressed as sperm motility when activated.	2010 Sep	20441800

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:03:16 UTC 2023` Edited by `admin` on `Fri Dec 15 15:03:16 UTC 2023`
Record UNII	18L31PSR28
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TRIMYRISTIN

Official Name

English

MYRISTIN

Common Name

English

TETRADECANOIC ACID, 1,1',1''-(1,2,3-PROPANETRIYL) ESTER

Common Name

English

DYNASAN 114

Common Name

English

GLYCERYL TRIMYRISTATE

Systematic Name

English

TRIMYRISTIN [INCI]

Common Name

English

NSC-4062

Code

English

TETRADECANOIC ACID, 1,2,3-PROPANETRIYL ESTER

Common Name

English

GLYCEROL TRIMYRISTATE

Systematic Name

English

TRIMYRISTIN [MI]

Common Name

English

1,2,3-PROPANETRIOL TRITETRADECANOATE

Systematic Name

English

TRIMYRISTIN [II]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C492