MIPOMERSEN SODIUM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Previously Marketed

First approved in 2013

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 11:08:15 GMT 2023` Edited by `admin` on `Sat Dec 16 11:08:15 GMT 2023`
Nucleic Acid Subtype
Sequence Type	OLIGONUCLEOTIDE
Record UNII	18EAY4870E
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MIPOMERSEN SODIUM

Official Name

English

MIPOMERSEN SODIUM SALT

Common Name

English

MIPOMERSEN SODIUM [VANDF]

Common Name

English

MIPOMERSEN SODIUM [USAN]

Common Name

English

Mipomersen sodium [WHO-DD]

Common Name

English

MIPOMERSEN SODIUM SALT [MI]

Common Name

English

ISIS 301012

Code

English

MIPOMERSEN SODIUM [ORANGE BOOK]

Common Name

English

ISIS-301012

Code

English

KYNAMRO

Brand Name

English

DNA, D(P-THIO)((2'-O-(MOE))RG-(2'-O-(MOE))RG-(2'-O-(MOE))RG-(2'-O-(MOE))RA-M5C-G-M5C-G-G-M5C-G-M5C-T-M5C-G-G-(2'-O-(MOE))M5RU-(2'-O-(MOE))M5RC-(2'-O-(MOE))RA-(2'-O-(MOE))M5RU), NONADECASODIUM SALT (MOE = 2-METHOXYETHYL)

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID20212108

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

DRUG BANK

DB05528

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

RXCUI

1367838

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

RxNorm

MESH

C524142

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

PUBCHEM

118984460

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

FDA UNII

18EAY4870E

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

ChEMBL

CHEMBL2219536

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

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NCI_THESAURUS

C166478

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

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MERCK INDEX

m7558

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

Merck Index

CAS

629167-92-6

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

DAILYMED

18EAY4870E

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

EVMPD

SUB115780

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

USAN

TT-31

Created by admin on Sat Dec 16 11:08:15 GMT 2023 , Edited by admin on Sat Dec 16 11:08:15 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
2-O-beta-hydroxy-ethoxy-methyl Ribose (Qiagen)	1_1-1_5;1_16-1_20	10 / 20
Deoxyribose (DNA)	1_6-1_15	10 / 20

Linkage	Site Range	Site Count
Sodium Phosporothioate	1_2-1_20	19 / 19

Related Record Type Details


					9GJ8S4GU0M

PARENT -> SALT/SOLVATE

Related Record Type Details


					9GJ8S4GU0M

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
BASE SUBSTITUTION	[1_12] [1_15]		CYTOSINE		5-METHYLCYTOSINE	6R795CQT4H

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:CALCULATED	CHEMICAL