MORPHERIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H30N2O3
Molecular Weight	346.4638
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)C1(CCN(CCN2CCOCC2)CC1)C3=CC=CC=C3

InChI

InChIKey=JDEDMCKQPKGSAX-UHFFFAOYSA-N

InChI=1S/C20H30N2O3/c1-2-25-19(23)20(18-6-4-3-5-7-18)8-10-21(11-9-20)12-13-22-14-16-24-17-15-22/h3-7H,2,8-17H2,1H3

HIDE SMILES / InChI

Molecular Formula	C20H30N2O3
Molecular Weight	346.4638
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13801235 | https://www.ncbi.nlm.nih.gov/pubmed/13304251

Morpheridine is a pethidine analog with strong analgesic activity. Morpheridine does not cause convulsions, although it produces the standard opioid side effects such as sedation and respiratory depression. Morpheridine is not currently used in medicine and is a Schedule I drug which is controlled under United Nations drug conventions.

Originator

Approval Year

PubMed

Title	Date	PubMed
Analgesic action of ethyl 4-phenylpiperidine-4-carboxylates with oxygenated 1-substituents.	1960 Jun	13801235

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:13:37 GMT 2025` Edited by `admin` on `Mon Mar 31 18:13:37 GMT 2025`
Record UNII	1854GKB41Y
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MORPHERIDINE

Official Name

English

IDS-NM-008

Preferred Name

English

1-(2-MORPHOLINOETHYL)-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER

Common Name

English

morpheridine [INN]

Common Name

English

MORPHERIDINE [MI]

Common Name

English

ISONIPECOTIC ACID, 1-(2-MORPHOLINOETHYL)-4-PHENYL-, ETHYL ESTER

Common Name

English

MORPHOLINOETHYL MORPETHIDINE

Common Name

English

4-PIPERIDINECARBOXYLIC ACID, 1-(2-(4-MORPHOLINYL)ETHYL)-4-PHENYL-, ETHYL ESTER

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241