ETHYL L-TYROSINATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H15NO3
Molecular Weight	209.2417
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)[C@@H](N)CC1=CC=C(O)C=C1

InChI

InChIKey=SBBWEQLNKVHYCX-JTQLQIEISA-N

InChI=1S/C11H15NO3/c1-2-15-11(14)10(12)7-8-3-5-9(13)6-4-8/h3-6,10,13H,2,7,12H2,1H3/t10-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C11H15NO3
Molecular Weight	209.2417
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.fishersci.com/shop/products/l-tyrosine-ethyl-ester-hydrochloride-99-1/AAA1835814 | https://www.genome.jp/dbget-bin/www_bget?dr:D09821

Tyrosine ethyl ester hydrochloride is used as a medical and organic intermediate and as an important amino protective agent. It is also used to introduce t-Boc protect gene. Tyrosine ethyl ester hydrochloride is used as a supplement (tyrosine).

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
thyroid hormone receptor binding 2 Target ID: GO:0046966 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1308155	Inhibitor 8297

PubMed

Title	Date	PubMed
Synthesis of 2-[18F]fluoro-L-tyrosine via regiospecific fluoro-de-stannylation.	2002 Aug	12150277
Light-driven tyrosine radical formation in a ruthenium-tyrosine complex attached to nanoparticle TiO2.	2002 Dec 2	12444768
Synthesis of gossypol atropisomers and derivatives and evaluation of their anti-proliferative and anti-oxidant activity.	2005 Jul 1	15878283
Singlet molecular oxygen [O2(1Deltag)]-mediated photodegradation of tyrosine derivatives in the presence of cationic and neutral micellar systems.	2008 Jun	17619119
Probing molecular motion by double-quantum (13C,13C) solid-state NMR spectroscopy: application to ubiquitin.	2010 Jan 13	20000710
High level production of bioactive di- and tri-tyrosine peptides by protease-catalyzed reactions.	2010 Nov	20868710
Mechanism of papain-catalyzed synthesis of oligo-tyrosine peptides.	2015 Jul-Aug	26047910

Patents

Sample Use Guides

In Vivo Use Guide

When male Sprague-Dawley rats were treated with 50 mg/kg L-tryptophan and Tyrosine ethyl ester 30 min prior to the intrahypothalamic injection of 2 ug amylin, brain tryptophan and tyrosine levels were selectively increased as compared to rats treated with amylin alone.

Route of Administration: Intraperitoneal

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:42:39 GMT 2023` Edited by `admin` on `Fri Dec 15 19:42:39 GMT 2023`
Record UNII	17RPW76A9G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETHYL L-TYROSINATE

Systematic Name

English

NSC-519993

Code

English

L-TYROSINE ETHYL ESTER

Systematic Name

English

Code System Code Type Description

CHEBI

9798