ETBX-061

Investigational

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 14:46:50 GMT 2023` Edited by `admin` on `Sat Dec 16 14:46:50 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	VIRUS
Source Materials Parent	`1SD7D21LO2` HUMAN ADENOVIRUS C SEROTYPE 5
Organism Family	Adenoviridae
Organism Genus	Mastadenovirus
Organism Species	human mastadenovirus c
Infraspecific Type	SEROTYPE:STRAIN
Infraspecific Name	TYPE 5:ETBX-061
Part	WHOLE
Record UNII	17K7SN702N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETBX-061

Common Name

English

AN ADENOVIRUS VECTOR CANCER VACCINE COMPOSED OF A REPLICATION-DEFECTIVE, SER OTYPE 5 ADENOVIRUS (AD5) THAT HAS BEEN MODIFIED BY REMOVAL OF THE E1, E2B AND E3 GENES AND INSERTION OF A MODIFIED HUMAN MUCIN 1 GENE ENCODING AGONIST EPITOPES DESIGNED TO INCRE

Common Name

English

ADENOVIRAL BRACHYURY VACCINE ETBX-061

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C143035

Created by admin on Sat Dec 16 14:46:50 GMT 2023 , Edited by admin on Sat Dec 16 14:46:50 GMT 2023

PRIMARY

CAS

2171550-29-9

Created by admin on Sat Dec 16 14:46:50 GMT 2023 , Edited by admin on Sat Dec 16 14:46:50 GMT 2023

PRIMARY

FDA UNII

17K7SN702N

Created by admin on Sat Dec 16 14:46:50 GMT 2023 , Edited by admin on Sat Dec 16 14:46:50 GMT 2023

PRIMARY

Related Record Type Details


					Z1N4MKK76U

MODIFIED MUCIN-1

EXPRESSED PROTEIN->VECTOR

Amount:

Structural Modifications

Modification Type	Location Type	Fragment Name	Fragment Approval
PROTEIN NOT EXPRESSED	viral genes early 2b	DNA POLYMERASE (HUMAN ADENOVIRUS 5)	ETQ2WKD05X
PROTEIN NOT EXPRESSED	viral genes early 2b	PRETERMINAL PROTEIN (HUMAN ADENOVIRUS 5)	PL0VT48B2N
PROTEIN NOT EXPRESSED	viral genes early 1	EARLY E1A PROTEIN (HUMAN ADENOVIRUS 5)	MW6YY4WVP4
VECTOR EXPRESSED PROTEIN	VIRAL GENE EARLY 1 (E1) REGION	MODIFIED MUCIN-1	Z1N4MKK76U