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Details

Stereochemistry ABSOLUTE
Molecular Formula C48H78O20
Molecular Weight 975.1209
Optical Activity UNSPECIFIED
Defined Stereocenters 26 / 26
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ASIATICOSIDE B

SMILES

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@H](OC[C@H]3O[C@@H](OC(=O)[C@]45CCC(C)(C)C[C@H]4C6=CC[C@@H]7[C@@]8(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]8[C@H](O)C[C@@]7(C)[C@]6(C)CC5)[C@H](O)[C@@H](O)[C@@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@H](O)[C@H]1O

InChI

InChIKey=NNWMHSNRRWMMBI-PJISEHJASA-N
InChI=1S/C48H78O20/c1-20-28(53)30(55)33(58)40(64-20)67-36-25(17-49)65-39(35(60)32(36)57)63-18-26-29(54)31(56)34(59)41(66-26)68-42(62)48-12-10-43(2,3)14-22(48)21-8-9-27-44(4)15-24(52)38(61)45(5,19-50)37(44)23(51)16-47(27,7)46(21,6)11-13-48/h8,20,22-41,49-61H,9-19H2,1-7H3/t20-,22-,23+,24+,25+,26+,27+,28-,29+,30+,31-,32+,33+,34+,35+,36+,37+,38-,39+,40-,41-,44+,45-,46+,47+,48-/m0/s1

HIDE SMILES / InChI
Molecular Formula C48H78O20
Molecular Weight 975.1209
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 26 / 26
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Asiaticoside B (TERMINOLOSIDE) was isolated from the roots of Cimicifuga foetida and roots/rhizomes extract of Actaea asiatica. It was found, that asiaticoside B had notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
New 9, 19-cycloartane triterpenoid from the root of Cimicifuga foetida.
2014-04
Cytotoxic cycloartane triterpene saponins from Actaea asiatica.
2006-10
Patents

Patents

US20090324526
1

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 23:30:17 GMT 2025
Edited
by admin
on Mon Mar 31 23:30:17 GMT 2025
Record UNII
17E01H280E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ASIATICOSIDE B
Common Name English
ASIATICOSIDE B (CONSTITUENT OF CENTELLA ASIATICA) [DSC]
Preferred Name English
OLEAN-12-EN-28-OIC ACID, 2,3,6,23-TETRAHYDROXY-, O-6-DEOXY-.ALPHA.-L-MANNOPYRANOSYL-(1->4)-O-.BETA.-D-GLUCOPYRANOSYL-(1->6)-.BETA.-D-GLUCOPYRANOSYL ESTER, (2.ALPHA.,3.BETA.,4.ALPHA.,6.BETA.)-
Systematic Name English
TERMINOLOSIDE
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID101317354
Created by admin on Mon Mar 31 23:30:17 GMT 2025 , Edited by admin on Mon Mar 31 23:30:17 GMT 2025
PRIMARY
CAS
125265-68-1
Created by admin on Mon Mar 31 23:30:17 GMT 2025 , Edited by admin on Mon Mar 31 23:30:17 GMT 2025
PRIMARY
FDA UNII
17E01H280E
Created by admin on Mon Mar 31 23:30:17 GMT 2025 , Edited by admin on Mon Mar 31 23:30:17 GMT 2025
PRIMARY
PUBCHEM
91618002
Created by admin on Mon Mar 31 23:30:17 GMT 2025 , Edited by admin on Mon Mar 31 23:30:17 GMT 2025
PRIMARY
NIH
NCATS
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