NAPORAFENIB

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H25F3N4O4
Molecular Weight	502.4856
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC=C(NC(=O)C2=CC=NC(=C2)C(F)(F)F)C=C1C3=CC(OCCO)=NC(=C3)N4CCOCC4

InChI

InChIKey=UEPXBTCUIIGYCY-UHFFFAOYSA-N

InChI=1S/C25H25F3N4O4/c1-16-2-3-19(30-24(34)17-4-5-29-21(12-17)25(26,27)28)15-20(16)18-13-22(32-6-9-35-10-7-32)31-23(14-18)36-11-8-33/h2-5,12-15,33H,6-11H2,1H3,(H,30,34)

HIDE SMILES / InChI

Molecular Formula	C25H25F3N4O4
Molecular Weight	502.4856
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:40:32 UTC 2023` Edited by `admin` on `Sat Dec 16 10:40:32 UTC 2023`
Record UNII	15JL80DG6H
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NAPORAFENIB

Official Name

English

LXH-254

Code

English

PAN-RAF INHIBITOR LXH254

Code

English

LXH254

Code

English

N-(3-(2-(HYDROXYETHOXY)-6-(MORPHOLIN-4-YL) PYRIDIN-4-YL)-4-METHYLPHENYL)-2-(TRIFLUOROMETHYL)PYRIDINE-4-CARBOXAMIDE

Systematic Name

English

naporafenib [INN]

Common Name

English

4-PYRIDINECARBOXAMIDE, N-(3-(2-(2-HYDROXYETHOXY)-6-(4-MORPHOLINYL)-4-PYRIDINYL)-4-METHYLPHENYL)-2-(TRIFLUOROMETHYL)-)-

Systematic Name

English

Naporafenib [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129825