4-GUANIDINOBUTYRIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H11N3O2
Molecular Weight	145.1597
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=N)NCCCC(O)=O

InChI

InChIKey=TUHVEAJXIMEOSA-UHFFFAOYSA-N

InChI=1S/C5H11N3O2/c6-5(7)8-3-1-2-4(9)10/h1-3H2,(H,9,10)(H4,6,7,8)

HIDE SMILES / InChI

Molecular Formula	C5H11N3O2
Molecular Weight	145.1597
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Guanidino compounds as cause of cardiovascular damage in chronic kidney disease: an in vitro evaluation.	2010	21079396
The orally active antihyperglycemic drug beta-guanidinopropionic acid is transported by the human proton-coupled amino acid transporter hPAT1.	2009-04-11	19358571
Detection of an L-amino acid dehydrogenase activity in Synechocystis sp. PCC 6803.	2009	19213808
Neurotransmitter alterations in embryonic succinate semialdehyde dehydrogenase (SSADH) deficiency suggest a heightened excitatory state during development.	2008-11-28	19040727
Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis sp. PCC 6803.	2007-11-28	18045455
Anisoin: a useful pre-chromatographic derivatization fluorogenic reagent for LC analysis of guanidino compounds.	2006-09-11	16460903
Biodegradability of end-groups of the biocide polyhexamethylene biguanide (PHMB) assessed using model compounds.	2006-08	16683128
Increased guanidino species in murine and human succinate semialdehyde dehydrogenase (SSADH) deficiency.	2006-04	16504488
On the role of arginine-glutamic acid ion pair in the ATP hydrolysis.	2006-01-01	16182434
Pseudomonas aeruginosa PAO1 genes for 3-guanidinopropionate and 4-guanidinobutyrate utilization may be derived from a common ancestor.	2005-12	16339950
Influence of 4-guanidinobutyric acid as coadsorbent in reducing recombination in dye-sensitized solar cells.	2005-11-24	16853833
A role for guanidino compounds in the brain.	2003-02	12701810
Dehydration modifies guanidino compound concentrations in the different zones of the rat kidney.	2002-05	11976926
The effect of high protein diet on urea and guanidino compound levels in renal insufficient mice.	2001-12	11858699
Long-term effect of partial nephrectomy on biological parameters, kidney histology, and guanidino compound levels in mice.	2001-12	11735086
Influence of 72% injury in one kidney on several organs involved in guanidino compound metabolism: a time course study.	2001-07	11510889
Transport and metabolism of agmatine in rat hepatocyte cultures.	2001-02	11179960
Guanidino compounds in serum and urine of cirrhotic patients.	1995-05	7752905
Guanidino compounds in hyperargininemia.	1987-11	3433275
Guanidino compounds in serum and cerebrospinal fluid of non-dialyzed patients with renal insufficiency.	1987-07-30	3665089
Guanidino compounds in plasma, urine and cerebrospinal fluid of hyperargininemic patients during therapy.	1985-02-28	3987036

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:17:00 GMT 2025` Edited by `admin` on `Mon Mar 31 19:17:00 GMT 2025`
Record UNII	15ADP48O8Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

4-GUANIDINOBUTYRIC ACID

Systematic Name

English

HL 6450

Preferred Name

English

BUTANOIC ACID, 4-((AMINOIMINOMETHYL)AMINO)-

Common Name

English

NSC-521717

Code

English

N-(4-BUTANOIC ACID)GUANIDINE

Common Name

English

.GAMMA.-GUANIDINEBUTYRIC ACID

Common Name

English

.GAMMA.-GUANIDINOBUTYRATE

Systematic Name

English

Code System Code Type Description

FDA UNII

15ADP48O8Q