4-GUANIDINOBUTYRIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H11N3O2
Molecular Weight	145.1597
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=N)NCCCC(O)=O

InChI

InChIKey=TUHVEAJXIMEOSA-UHFFFAOYSA-N

InChI=1S/C5H11N3O2/c6-5(7)8-3-1-2-4(9)10/h1-3H2,(H,9,10)(H4,6,7,8)

HIDE SMILES / InChI

Molecular Formula	C5H11N3O2
Molecular Weight	145.1597
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Guanidino compounds in plasma, urine and cerebrospinal fluid of hyperargininemic patients during therapy.	1985 Feb 28	3987036
Guanidino compounds in serum and cerebrospinal fluid of non-dialyzed patients with renal insufficiency.	1987 Jul 30	3665089
Guanidino compounds in hyperargininemia.	1987 Nov	3433275
Guanidino compounds in serum and urine of cirrhotic patients.	1995 May	7752905
The effect of high protein diet on urea and guanidino compound levels in renal insufficient mice.	2001 Dec	11858699
Long-term effect of partial nephrectomy on biological parameters, kidney histology, and guanidino compound levels in mice.	2001 Dec	11735086
Transport and metabolism of agmatine in rat hepatocyte cultures.	2001 Feb	11179960
Influence of 72% injury in one kidney on several organs involved in guanidino compound metabolism: a time course study.	2001 Jul	11510889
Dehydration modifies guanidino compound concentrations in the different zones of the rat kidney.	2002 May	11976926
A role for guanidino compounds in the brain.	2003 Feb	12701810
Pseudomonas aeruginosa PAO1 genes for 3-guanidinopropionate and 4-guanidinobutyrate utilization may be derived from a common ancestor.	2005 Dec	16339950
Influence of 4-guanidinobutyric acid as coadsorbent in reducing recombination in dye-sensitized solar cells.	2005 Nov 24	16853833
Increased guanidino species in murine and human succinate semialdehyde dehydrogenase (SSADH) deficiency.	2006 Apr	16504488
Biodegradability of end-groups of the biocide polyhexamethylene biguanide (PHMB) assessed using model compounds.	2006 Aug	16683128
On the role of arginine-glutamic acid ion pair in the ATP hydrolysis.	2006 Jan 1	16182434
Anisoin: a useful pre-chromatographic derivatization fluorogenic reagent for LC analysis of guanidino compounds.	2006 Sep 11	16460903
Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis sp. PCC 6803.	2007 Nov 28	18045455
Neurotransmitter alterations in embryonic succinate semialdehyde dehydrogenase (SSADH) deficiency suggest a heightened excitatory state during development.	2008 Nov 28	19040727
Detection of an L-amino acid dehydrogenase activity in Synechocystis sp. PCC 6803.	2009	19213808
The orally active antihyperglycemic drug beta-guanidinopropionic acid is transported by the human proton-coupled amino acid transporter hPAT1.	2009 May-Jun	19358571
Guanidino compounds as cause of cardiovascular damage in chronic kidney disease: an in vitro evaluation.	2010	21079396

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:37:00 GMT 2023` Edited by `admin` on `Fri Dec 15 18:37:00 GMT 2023`
Record UNII	15ADP48O8Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

4-GUANIDINOBUTYRIC ACID

Systematic Name

English

BUTANOIC ACID, 4-((AMINOIMINOMETHYL)AMINO)-

Common Name

English

NSC-521717

Code

English

HL 6450

Code

English

N-(4-BUTANOIC ACID)GUANIDINE

Common Name

English

.GAMMA.-GUANIDINEBUTYRIC ACID

Common Name

English

.GAMMA.-GUANIDINOBUTYRATE

Systematic Name

English

Code System Code Type Description

FDA UNII

15ADP48O8Q