DIPICRYLAMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H5N7O12
Molecular Weight	439.2078
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O-][N+](=O)C1=CC(=C(NC2=C(C=C(C=C2[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O)C(=C1)[N+]([O-])=O)[N+]([O-])=O

InChI

InChIKey=CBCIHIVRDWLAME-UHFFFAOYSA-N

InChI=1S/C12H5N7O12/c20-14(21)5-1-7(16(24)25)11(8(2-5)17(26)27)13-12-9(18(28)29)3-6(15(22)23)4-10(12)19(30)31/h1-4,13H

HIDE SMILES / InChI

Molecular Formula	C12H5N7O12
Molecular Weight	439.2078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Metallothionein, zinc, and mercury levels in tissues of young rats exposed to zinc and subsequently to mercury.	2007 Sep 29	17916369
Identification and expression profile of gene transcripts differentially expressed during metallic exposure in Eisenia fetida coelomocytes.	2008	18634820
Modulation of Nrf2-dependent antioxidant functions in the RPE by Zip2, a zinc transporter protein.	2008 Apr	18385089
A combined patch-clamp and electrorotation study of the voltage- and frequency-dependent membrane capacitance caused by structurally dissimilar lipophilic anions.	2008 Jan	18197354
Rational optimization and imaging in vivo of a genetically encoded optical voltage reporter.	2008 May 21	18495892
Zinc triggers microglial activation.	2008 May 28	18509044
Effects of diallyl sulfide and zinc on testicular steroidogenesis in cadmium-treated male rats.	2008 Sep-Oct	18972399
Laser spectroscopy for atmospheric and environmental sensing.	2009	22303184
Cloning, expression, and characterization of cadmium-induced metallothionein-2 from the earthworms Metaphire posthuma and Polypheretima elongata.	2009 Apr	18834958
The cation diffusion facilitator gene cdf-2 mediates zinc metabolism in Caenorhabditis elegans.	2009 Aug	19448268
Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha.	2009 Aug 28	19714248
Pannexin-1-dependent caspase-1 activation and secretion of IL-1beta is regulated by zinc.	2009 Feb	19130485
Identification of tumor promotion marker genes for predicting tumor promoting potential of chemicals in BALB/c 3T3 cells.	2009 Feb	19000923
Spectroscopic and electrochemical analysis of psychotropic drugs.	2009 Jan	20177449
Effect of zinc exposure on HNE and GLT-1 in spinal cord culture.	2009 Jan	19061913
Submillisecond optical reporting of membrane potential in situ using a neuronal tracer dye.	2009 Jul 22	19625510
Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents.	2009 Jun 15	19303893
Zinc reverses malathion-induced impairment in antioxidant defenses.	2009 Jun 22	19429256
Inhibition of poly(ADP-ribose) polymerase-1 by arsenite interferes with repair of oxidative DNA damage.	2009 Mar 13	19056730
Analysis of differential gene-regulatory responses to zinc in human intestinal and placental cell lines.	2009 May	18947441
Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution.	2009 May 2	19428942
1,10-phenanthroline stabilizes mRNA of the carcinogen-metabolizing enzyme, cytochrome P450 1a1.	2010 Feb 1	19896525
Rearrangements in the KcsA cytoplasmic domain underlie its gating.	2010 Feb 5	19959477
Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.	2010 Jan 15	19835899
c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.	2010 Jul	20423716
ERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity.	2010 Jul	20412391
Zinc deficiency suppresses matrix mineralization and retards osteogenesis transiently with catch-up possibly through Runx 2 modulation.	2010 Mar	19913120
Cadmium down-regulation of kidney Sp1 binding to mouse SGLT1 and SGLT2 gene promoters: possible reaction of cadmium with the zinc finger domain of Sp1.	2010 May 1	20060848
Can metal stress induce transferable changes in gene transcription in Daphnia magna?	2010 May 5	19683351
Glucose exacerbates zinc-induced astrocyte death.	2010 Nov 10	20800666
Complex role of zinc in methamphetamine toxicity in vitro.	2010 Nov 24	20801194
Zinc prevents the copper-induced damage of cultured astrocytes.	2010 Oct	20600438
Recordings from human myenteric neurons using voltage-sensitive dyes.	2010 Oct 15	20691728
Improved probes for hybrid voltage sensor imaging.	2010 Oct 6	20923671
LPS-induced decrease in intracellular labile zinc, [Zn]i, contributes to apoptosis in cultured sheep pulmonary artery endothelial cells.	2011 Apr	21239534
Microglial zinc uptake via zinc transporters induces ATP release and the activation of microglia.	2011 Dec	22253048
Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation.	2011 Dec	22202117
Dietary catechins and procyanidins modulate zinc homeostasis in human HepG2 cells.	2011 Feb	20471814
Increased level of exogenous zinc induces cytotoxicity and up-regulates the expression of the ZnT-1 zinc transporter gene in pancreatic cancer cells.	2011 Jan	20392624
Signaling cascades mediate astrocyte death induced by zinc.	2011 Jul 28	21575692
Nodal-mediated epigenesis requires dynamin-mediated endocytosis.	2011 Mar	21337468
Delayed biochemical changes induced by mercury intoxication are prevented by zinc pre-exposure.	2011 Mar	21183220
Zinc-chelation contributes to the anti-angiogenic effect of ellagic acid on inhibiting MMP-2 activity, cell migration and tube formation.	2011 May 4	21573219
Zinc, cadmium and nickel increase the activation of NF-κB and the release of cytokines from THP-1 monocytic cells.	2011 Nov	21842098
TACE/TGF-α/EGFR regulates CXCL8 in bronchial epithelial cells exposed to particulate matter components.	2011 Nov	21540303
Zinc at cytotoxic concentrations affects posttranscriptional events of gene expression in cancer cells.	2012	22415087
Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1.	2012 Aug 31	22736759
Mercury chloride increases hepatic alanine aminotransferase and glucose 6-phosphatase activities in newborn rats in vivo.	2012 Jun 1	22413763
Molecular characterization of a catalase from Hydra vulgaris.	2012 Jun 15	22521743
Proteomic discovery of biomarkers of metal contamination in Sydney Rock oysters (Saccostrea glomerata).	2012 Mar	22030410

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:36:14 GMT 2023` Edited by `admin` on `Sat Dec 16 01:36:14 GMT 2023`
Record UNII	14STR4KG8T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIPICRYLAMINE

Common Name

English

NSC-1786

Code

English

HEXANITRODIPHENYLAMINE

Common Name

English

DIPICRYLAMINE [MI]

Common Name

English

Code System Code Type Description

PUBCHEM

8576