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Details

Stereochemistry ACHIRAL
Molecular Formula C2H2N2S
Molecular Weight 86.116
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,3,4-THIADIAZOLE

SMILES

S1C=NN=C1

InChI

InChIKey=MBIZXFATKUQOOA-UHFFFAOYSA-N
InChI=1S/C2H2N2S/c1-3-4-2-5-1/h1-2H

HIDE SMILES / InChI

Molecular Formula C2H2N2S
Molecular Weight 86.116
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
6-(4-Chloro-phen-yl)-2-isobutyl-imidazo[2,1-b][1,3,4]thia-diazole.
2010-12-24
2-Methyl-5-[(3-methyl-4-nitro-benz-yl)sulfan-yl]-1,3,4-thia-diazole.
2010-12-24
5-[(4-Meth-oxy-benz-yl)sulfan-yl]-2-methyl-1,3,4-thia-diazole.
2010-12-18
Bis[(5-phenyl-1,3,4-thia-diazol-2-yl)sulfan-yl]methane.
2010-11-06
Synthesis, antioxidant activities and urease inhibition of some new 1,2,4-triazole and 1,3,4-thiadiazole derivatives.
2010-11
Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities.
2010-11
(14)N NQR, (1)H NMR and DFT/QTAIM study of hydrogen bonding and polymorphism in selected solid 1,3,4-thiadiazole derivatives.
2010-10-28
3-Ethyl-6-[3-(4-fluoro-phen-yl)-1H-pyrazol-4-yl]-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.
2010-10-13
Investigation of the toxic functional group of cephalosporins by zebrafish embryo toxicity test.
2010-10
Urea-type ligand-modified CdSe quantum dots as a fluorescence "turn-on" sensor for CO3(2-) anions.
2010-09-24
Synthesis and Antibacterial and Antifungal Studies of Novel Nitrogen Containing Heterocycles from 5-Ethylpyridin-2-ethanol.
2010-09
Synthesis and bioassay of aminosulfonyl-1,3,4-oxadiazoles and their interconversion to 1,3,4-thiadiazoles.
2010-09
Synthesis and evaluation of anti-Toxoplasma gondii and antimicrobial activities of thiosemicarbazides, 4-thiazolidinones and 1,3,4-thiadiazoles.
2010-09
Synthesis and pharmacological evaluation of condensed heterocyclic 6-substituted 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives of isoniazid.
2010-08-15
Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: from docking false positives to ATP-noncompetitive inhibitors.
2010-08-02
Homology modeling and QSAR analysis of 1,3,4-thiadiazole and 1,3,4-triazole derivatives as carbonic anhydrase inhibitors.
2010-08
2-(4-Fluoro-benzyl-idene)-N-(4-meth-oxy-benzylidene)-1,3,4-thia-diazol-2-amine.
2010-06-18
Comparative studies of mercapto thiadiazoles self-assembled on gold nanoparticle as ionophores for Cu(II) carbon paste sensors.
2010-04-30
Synthesis and anti-inflammatory evaluation of some condensed [4-(3,4-dimethylphenyl)-1(2H)-oxo-phthalazin-2-yl]acetic acid hydrazide.
2010-04
Novel C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents: 1,3,4-Thiadiazolylmethylphenyl glucoside congeners.
2010-03-15
Synthesis and antimicrobial activity evaluation of new 1,2,4-triazoles and 1,3,4-thiadiazoles bearing imidazo[2,1-b]thiazole moiety.
2010-01
Synthesis and antimicrobial activity of 3-(1,3,4-Oxadiazol-2-yl)quinazolin-4(3H)-ones.
2009-12-17
Vanadium-induced formation of thiadiazole and thiazoline compounds. Mononuclear and dinuclear oxovanadium(v) complexes with open-chain and cyclized thiosemicarbazone ligands.
2009-11-28
2-Substituted-5-nitroheterocycles: in vitro anti-Helicobacter pylori activity and structure-activity relationship study.
2009-11
N,N-Bis(2,6-difluoro-benz-yl)-1,3,4-thia-diazol-2-amine.
2009-08-15
Methylsulfonylpyrazolyl oxadiazoles and thiadiazoles as potent, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity.
2009-08
Synthesis and biological activity of some new 1,3,4-thiadiazole and 1,2,4-triazole compounds containing a phenylalanine moiety.
2009-07-16
A one-dimensional cadmium(II) complex supported by a sulfur-nitro-gen mixed-donor ligand.
2009-06-27
5-(3-Fluoro-phen-yl)-1,3,4-thia-diazol-2-amine.
2009-05-29
5-(2-Methyl-phen-yl)-1,3,4-thia-diazol-2-amine.
2009-04-02
Synthesis of 1,3,4-thiadiazole derivatives as aminopeptidase N inhibitors.
2009-02
2-Benzoyl-amino-N-[5-(4-bromo-phen-yl)-1,3,4-thia-diazol-2-yl]ethanamide.
2009-01-17
A high throughput serum paraoxonase assay for discovery of small molecule modulators of PON1 activity.
2008-11-26
3,4,5-Trimethoxy-benzohydrazidium chloride.
2008-11-13
1-(4-Methyl-benzo-yl)-3-[5-(4-pyrid-yl)-1,3,4-thia-diazol-2-yl]urea.
2008-11-08
N-[4-Acetyl-5-(3-methoxy-phen-yl)-4,5-dihydro-1,3,4-thia-diazol-2-yl]acetamide.
2008-10-11
6-(4-Methyl-phen-yl)-3-(3,4,5-trimethoxy-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole.
2008-09-30
(2R)-N-[5-(4-Chloro-phen-yl)-1,3,4-thia-diazol-2-yl]-2-(cinnamoylamino)propanamide.
2008-09-24
(2R)-2-Cinnamoylamino-N-[5-(4-methoxy-phen-yl)-1,3,4-thia-diazol-2-yl]propanamide.
2008-09-06
Synthesis and Biological Screening of 5-{[(4,6-Disubstituted pyrimidine-2-yl)thio]methyl}-N-phenyl-1,3,4-thiadiazol-2-amines.
2008-09
6-(4-Pyrid-yl)-3-(3,4,5-trimethoxy-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.
2008-07-31
3,6-Bis(3,4,5-trimethoxy-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.
2008-07-23
6-(2-Methyl-phen-yl)-3-(3,4,5-trimethoxy-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.
2008-07-12
6-(3-Pyrid-yl)-3-(3,4,5-trimethoxy-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.
2008-07-05
3-[1-(4-Isobutyl-phen-yl)eth-yl]-6-(4-methyl-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.
2008-05-14
3-(2-Fluoro-phen-yl)-6-(phenoxy-meth-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.
2008-03-12
Some QSAR studies for a group of sulfonamide Schiff base as carbonic anhydrase CA II inhibitors.
2008-02
3,3-Dimethyl-1-[5-(1H-1,2,4-triazol-1-yl-meth-yl)-1,3,4-thia-diazol-2-ylsulfan-yl]butan-2-one.
2008-01-09
Ethyl 5-[6-(furan-2-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazol-3-yl]-2,6-di-methylnicotinate.
2007-12-06
N-[1-(5-Acetamido-3-acetyl-2-methyl-2,3-dihydro-1,3,4-thia-diazol-2-yl)-2-phenyl-ethyl]acetamide.
2007-12-06
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:11:51 GMT 2025
Edited
by admin
on Mon Mar 31 19:11:51 GMT 2025
Record UNII
14IAC3GH7G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1,3,4-THIADIAZOLE
Systematic Name English
THIADIAZOLE
Preferred Name English
THIADIAZOLE, 1,3,4-
Systematic Name English
Code System Code Type Description
FDA UNII
14IAC3GH7G
Created by admin on Mon Mar 31 19:11:51 GMT 2025 , Edited by admin on Mon Mar 31 19:11:51 GMT 2025
PRIMARY
CAS
289-06-5
Created by admin on Mon Mar 31 19:11:51 GMT 2025 , Edited by admin on Mon Mar 31 19:11:51 GMT 2025
PRIMARY
CHEBI
39467
Created by admin on Mon Mar 31 19:11:51 GMT 2025 , Edited by admin on Mon Mar 31 19:11:51 GMT 2025
PRIMARY
MESH
C058949
Created by admin on Mon Mar 31 19:11:51 GMT 2025 , Edited by admin on Mon Mar 31 19:11:51 GMT 2025
PRIMARY
EPA CompTox
DTXSID00183089
Created by admin on Mon Mar 31 19:11:51 GMT 2025 , Edited by admin on Mon Mar 31 19:11:51 GMT 2025
PRIMARY
PUBCHEM
119391
Created by admin on Mon Mar 31 19:11:51 GMT 2025 , Edited by admin on Mon Mar 31 19:11:51 GMT 2025
PRIMARY
CHEBI
39472
Created by admin on Mon Mar 31 19:11:51 GMT 2025 , Edited by admin on Mon Mar 31 19:11:51 GMT 2025
PRIMARY