ETHYLHEXYLGLYCERIN

Possibly Marketed Outside US

Details

Stereochemistry	MIXED
Molecular Formula	C11H24O3
Molecular Weight	204.3065
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC(CC)COCC(O)CO

InChI

InChIKey=NCZPCONIKBICGS-UHFFFAOYSA-N

InChI=1S/C11H24O3/c1-3-5-6-10(4-2)8-14-9-11(13)7-12/h10-13H,3-9H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C11H24O3
Molecular Weight	204.3065
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/26876063 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082626

Ethylhexylglycerin (EHG) is a glyceryl ether that is commonly used as a preservative in cosmetics. EHG acts as a a surfactant, reducing surface tension) and emollient, softening and conditioning the skin. EHG has been shown to have antimicrobial properties, and has occasionally been reported as a contact allergen.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Acne 100 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=636ceab4-b6f2-4198-9574-94f123a5299b	Inactive ingredient		Approved 8583	24 HOUR PIMPLE PUNISHER Approved Use For treatment of Acne. Helps keep skin clear of new acne blemishes.

Doses

Dose	Population	Adverse events
10 % single, topical Highest recorded dose Dose: 10 % Route: topical Route: single Dose: 10 % Sources: https://pubmed.ncbi.nlm.nih.gov/26876063/	unhealthy Health Status: unhealthy Sex: F Food Status: UNKNOWN Sources: https://pubmed.ncbi.nlm.nih.gov/26876063/	Other AEs: Contact dermatitis... Other AEs: Contact dermatitis Sources: https://pubmed.ncbi.nlm.nih.gov/26876063/

AEs

AE	Significance	Dose	Population
Contact dermatitis		10 % single, topical Highest recorded dose Dose: 10 % Route: topical Route: single Dose: 10 % Sources: https://pubmed.ncbi.nlm.nih.gov/26876063/	unhealthy Health Status: unhealthy Sex: F Food Status: UNKNOWN Sources: https://pubmed.ncbi.nlm.nih.gov/26876063/

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:12:01 GMT 2025` Edited by `admin` on `Mon Mar 31 18:12:01 GMT 2025`
Record UNII	147D247K3P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETHYLHEXYLGLYCERIN

Official Name

English

1,2-PROPANEDIOL, 3-((2-ETHYLHEXYL)OXY)-

Preferred Name

English

ETHYLHEXYLGLYCERIN [MART.]

Common Name

English

Ethylhexylglycerin [WHO-DD]

Common Name

English

OCTOXYGLYCERIN

Systematic Name

English

Code System Code Type Description

FDA UNII

147D247K3P