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Details

Stereochemistry ACHIRAL
Molecular Formula 2C20H22ClN.C10H8O6S2
Molecular Weight 911.9976
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PYRROBUTAMINE NAPHTHALENE DISULFONATE

SMILES

c1ccc(cc1)C(=CCN2CCCC2)Cc3ccc(cc3)Cl.c1ccc(cc1)C(=CCN2CCCC2)Cc3ccc(cc3)Cl.c1cc2c(cccc2S(=O)(=O)O)c(c1)S(=O)(=O)O

InChI

InChIKey=OCOQSLMGOIWOJJ-UHFFFAOYSA-N
InChI=1S/2C20H22ClN.C10H8O6S2/c2*21-20-10-8-17(9-11-20)16-19(18-6-2-1-3-7-18)12-15-22-13-4-5-14-22;11-17(12,13)9-5-1-3-7-8(9)4-2-6-10(7)18(14,15)16/h2*1-3,6-12H,4-5,13-16H2;1-6H,(H,11,12,13)(H,14,15,16)

HIDE SMILES / InChI

Molecular Formula C10H8O6S2
Molecular Weight 288.2995
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C20H22ClN
Molecular Weight 311.8491
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

PYRROBUTAMINE is a potent H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate the inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Pyronil

Approved Use

Antihistaminic
PubMed

PubMed

TitleDatePubMed
Antihistaminic action of pyronil.
1952 Jul
Chemical and pharmacological characteristics of the antihistaminic compound, pyrrobutamine.
1953 Nov-Dec
Substance Class Chemical
Created
by admin
on Sat Jun 26 06:52:41 UTC 2021
Edited
by admin
on Sat Jun 26 06:52:41 UTC 2021
Record UNII
144X0H6HW6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PYRROBUTAMINE NAPHTHALENE DISULFONATE
Common Name English
PYRROLIDINE, 1-(4-(4-CHLOROPHENYL)-3-PHENYL-2-BUTENYL)-, 1,5-NAPHTHALENEDISULFONATE (2:1)
Common Name English
1,5-NAPHTHALENEDISULFONIC ACID, COMPD. WITH 1-(4-(4-CHLOROPHENYL)-3-PHENYL-2-BUTEN-1-YL)PYRROLIDINE (1:2)
Common Name English
1-(4-(4-CHLOROPHENYL)-3-PHENYL-2-BUTENYL)-PYRROLIDINE 1,5-NAPHTHALENEDISULFONATE
Systematic Name English
Code System Code Type Description
FDA UNII
144X0H6HW6
Created by admin on Sat Jun 26 06:52:41 UTC 2021 , Edited by admin on Sat Jun 26 06:52:41 UTC 2021
PRIMARY
RXCUI
1307555
Created by admin on Sat Jun 26 06:52:41 UTC 2021 , Edited by admin on Sat Jun 26 06:52:41 UTC 2021
PRIMARY RxNorm
CAS
93777-57-2
Created by admin on Sat Jun 26 06:52:41 UTC 2021 , Edited by admin on Sat Jun 26 06:52:41 UTC 2021
PRIMARY
PUBCHEM
73415764
Created by admin on Sat Jun 26 06:52:41 UTC 2021 , Edited by admin on Sat Jun 26 06:52:41 UTC 2021
PRIMARY
ECHA (EC/EINECS)
298-089-6
Created by admin on Sat Jun 26 06:52:41 UTC 2021 , Edited by admin on Sat Jun 26 06:52:41 UTC 2021
PRIMARY
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ACTIVE MOIETY