1,2-DIOXETANE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H4O2
Molecular Weight	60.052
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1COO1

InChI

InChIKey=BVTJGGGYKAMDBN-UHFFFAOYSA-N

InChI=1S/C2H4O2/c1-2-4-3-1/h1-2H2

HIDE SMILES / InChI

Molecular Formula	C2H4O2
Molecular Weight	60.052
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Singlet and triplet potential surfaces for the O2+C2H4 reaction.	2010-11-14	21073222
Experimental evidence of the occurrence of intramolecular electron transfer in catalyzed 1,2-dioxetane decomposition.	2010-10-01	20825174
Synthesis of thermally stable acylamino-substituted bicyclic dioxetanes and their base-induced chemiluminescent decomposition.	2010-09-03	20681740
Imaging beta-galactosidase activity in human tumor xenografts and transgenic mice using a chemiluminescent substrate.	2010-08-06	20700459
Characterization and validation of a chemiluminescent assay based on 1,2-dioxetanes for rapid detection of viable Escherichia coli.	2010-05	20217073
Self-cleavable chemiluminescent probes suitable for protease sensing.	2009-07-21	19582305
Generation of cholesterol carboxyaldehyde by the reaction of singlet molecular oxygen [O2 (1Delta(g))] as well as ozone with cholesterol.	2009-05	19358613
In search of a chemiluminescence 1,4-dioxy biradical.	2009-03-04	19206238
Chemiluminescence-based detection of gastrointestinal malignancies.	2009-02-26	19827005
Mechanism of efficient firefly bioluminescence via adiabatic transition state and seam of sloped conical intersection.	2008-10-01	18767834
Photooxygenation of 5-dialkylamino-4-pyrrolin-3-ones. Synthesis of highly functionalized ureas, 2-oxazolidinones, and 2-oxazolinones.	2008-09-05	18680344
Intensified biochip system using chemiluminescence for the detection of Bacillus globigii spores.	2008-07	18224472
Colour change of chemiluminescence for base-induced decomposition of dioxetane bearing a 4-(4-cyanophenyl)iminomethyl-3-hydroxyphenyl group.	2008-05-30	18509844
Influence of various combinations of mucolytic agent and non-ionic surfactant on intestinal absorption of poorly absorbed hydrophilic compounds.	2008-02-12	17869034
Weak chemiluminescence emission during base induced rearrangement of G-factors.	2008-02-07	18219413
Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function.	2008-01-22	18211691
Color modulation for intramolecular charge-transfer-induced chemiluminescence of 1,2-dioxetanes.	2008	18752319
Chemiluminescent probe for the in vitro detection of protease activity.	2007-11-08	17939676
Chemiluminescence of 1,2-dioxetane. Reaction mechanism uncovered.	2007-08-16	17636973
Sulfanyl radical promoted C4'-C5' bond scission of 5'-oxo-3',4'-didehydro-2',3'-dideoxynucleosides.	2006-10-21	17024279
[Chemiluminescent detection of E. coli O157:H7 in food based on magnetic enzyme-linked immuno method].	2006-05	16643808
Efficient photocatalytic oxygenation of aromatic alkene to 1,2-dioxetane with oxygen via electron transfer.	2005-09-15	16146403
Bicyclic dioxetanes bearing an inden-2-yl or a benzo(b)thiazol-2-yl moiety as a CIEEL-active chemiluminescent substrate emitting red light.	2005-04-02	15803504
Porous silicon-based biosensor for pathogen detection.	2005-02-15	15626624
Chemiluminescence in molecular recognition: base-induced decomposition of optically active dioxetanes bearing a bisnaphthol moiety with a complex of optically active crown ether-potassium tert-butoxide.	2005-02-14	15685346
Electronic substituent effects on the cleavage specificity of a non-heme Fe(2+)-dependent beta-diketone dioxygenase and their mechanistic implications.	2004-10-06	15453718
ZstatFlu-II test: a chemiluminescent neuraminidase assay for influenza viral diagnostics.	2003-04-18	12701088
Design and synthesis of chemiluminescent probes for the detection of cholinesterase activity.	2002-05-01	11971738
Finding the needle in the haystack: why high-throughput screening is good for your health.	2002	12100740
Design and synthesis of chemiluminescent substrates with high luminescent efficiency in an aqueous system: 5-tert-butyl-4,4-dimethyl-2,6,7-trioxabicyclo[3.2.0]heptanes bearing a 3-hydroxy-4-(1-iminoethyl)phenyl moiety at the 1-position.	2001-08-21	11512143
Dideoxy DNA sequencing with chemiluminescent detection.	2001-05	18265268

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:52:44 GMT 2025` Edited by `admin` on `Mon Mar 31 19:52:44 GMT 2025`
Record UNII	142GQA523X
Record Status	`Validated (UNII)`
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Name

Type

Language

1,2-DIOXETANE

Preferred Name

English

Code System Code Type Description

EPA CompTox

DTXSID20218105