1,2-DIOXETANE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H4O2
Molecular Weight	60.052
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1COO1

InChI

InChIKey=BVTJGGGYKAMDBN-UHFFFAOYSA-N

InChI=1S/C2H4O2/c1-2-4-3-1/h1-2H2

HIDE SMILES / InChI

Molecular Formula	C2H4O2
Molecular Weight	60.052
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Design and synthesis of chemiluminescent substrates with high luminescent efficiency in an aqueous system: 5-tert-butyl-4,4-dimethyl-2,6,7-trioxabicyclo[3.2.0]heptanes bearing a 3-hydroxy-4-(1-iminoethyl)phenyl moiety at the 1-position.	2001 Jul-Aug	11512143
Dideoxy DNA sequencing with chemiluminescent detection.	2001 May	18265268
Finding the needle in the haystack: why high-throughput screening is good for your health.	2002	12100740
Design and synthesis of chemiluminescent probes for the detection of cholinesterase activity.	2002 May 1	11971738
ZstatFlu-II test: a chemiluminescent neuraminidase assay for influenza viral diagnostics.	2003 May-Jun	12701088
Electronic substituent effects on the cleavage specificity of a non-heme Fe(2+)-dependent beta-diketone dioxygenase and their mechanistic implications.	2004 Oct 6	15453718
Chemiluminescence in molecular recognition: base-induced decomposition of optically active dioxetanes bearing a bisnaphthol moiety with a complex of optically active crown ether-potassium tert-butoxide.	2005 Feb 14	15685346
Porous silicon-based biosensor for pathogen detection.	2005 Feb 15	15626624
Bicyclic dioxetanes bearing an inden-2-yl or a benzo(b)thiazol-2-yl moiety as a CIEEL-active chemiluminescent substrate emitting red light.	2005 Mar-Apr	15803504
Efficient photocatalytic oxygenation of aromatic alkene to 1,2-dioxetane with oxygen via electron transfer.	2005 Sep 15	16146403
[Chemiluminescent detection of E. coli O157:H7 in food based on magnetic enzyme-linked immuno method].	2006 May	16643808
Sulfanyl radical promoted C4'-C5' bond scission of 5'-oxo-3',4'-didehydro-2',3'-dideoxynucleosides.	2006 Oct 21	17024279
Chemiluminescence of 1,2-dioxetane. Reaction mechanism uncovered.	2007 Aug 16	17636973
Chemiluminescent probe for the in vitro detection of protease activity.	2007 Nov 8	17939676
Color modulation for intramolecular charge-transfer-induced chemiluminescence of 1,2-dioxetanes.	2008	18752319
Influence of various combinations of mucolytic agent and non-ionic surfactant on intestinal absorption of poorly absorbed hydrophilic compounds.	2008 Feb 12	17869034
Weak chemiluminescence emission during base induced rearrangement of G-factors.	2008 Feb 7	18219413
Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function.	2008 Jan 22	18211691
Intensified biochip system using chemiluminescence for the detection of Bacillus globigii spores.	2008 Jul	18224472
Mechanism of efficient firefly bioluminescence via adiabatic transition state and seam of sloped conical intersection.	2008 Oct 1	18767834
Photooxygenation of 5-dialkylamino-4-pyrrolin-3-ones. Synthesis of highly functionalized ureas, 2-oxazolidinones, and 2-oxazolinones.	2008 Sep 5	18680344
Colour change of chemiluminescence for base-induced decomposition of dioxetane bearing a 4-(4-cyanophenyl)iminomethyl-3-hydroxyphenyl group.	2008 Sep-Oct	18509844
Self-cleavable chemiluminescent probes suitable for protease sensing.	2009 Jul 21	19582305
In search of a chemiluminescence 1,4-dioxy biradical.	2009 Mar 4	19206238
Generation of cholesterol carboxyaldehyde by the reaction of singlet molecular oxygen [O2 (1Delta(g))] as well as ozone with cholesterol.	2009 May	19358613
Imaging beta-galactosidase activity in human tumor xenografts and transgenic mice using a chemiluminescent substrate.	2010 Aug 6	20700459
Characterization and validation of a chemiluminescent assay based on 1,2-dioxetanes for rapid detection of viable Escherichia coli.	2010 May	20217073
Singlet and triplet potential surfaces for the O2+C2H4 reaction.	2010 Nov 14	21073222
Chemiluminescence-based detection of gastrointestinal malignancies.	2010 Nov-Dec	19827005
Experimental evidence of the occurrence of intramolecular electron transfer in catalyzed 1,2-dioxetane decomposition.	2010 Oct 1	20825174
Synthesis of thermally stable acylamino-substituted bicyclic dioxetanes and their base-induced chemiluminescent decomposition.	2010 Sep 3	20681740

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:39:55 UTC 2023` Edited by `admin` on `Fri Dec 15 19:39:55 UTC 2023`
Record UNII	142GQA523X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,2-DIOXETANE

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID20218105