FOSAZEPAM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H18ClN2O2P
Molecular Weight	360.774
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CP(C)(=O)CN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C3=CC=CC=C3

InChI

InChIKey=JMYCGCXYZZHWMO-UHFFFAOYSA-N

InChI=1S/C18H18ClN2O2P/c1-24(2,23)12-21-16-9-8-14(19)10-15(16)18(20-11-17(21)22)13-6-4-3-5-7-13/h3-10H,11-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C18H18ClN2O2P
Molecular Weight	360.774
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Effect of diazepam and fosazepam (a soluble derivative of diazepam) on sleep in man.	1976 Aug	22216491
Anxiety and sleep after fosazepam.	1976 Feb	184806
Efficacy and side effects of flurazepam, fosazepam, and nitrazepam as sleeping aids in psychogeriatric patients.	1978 Jan	24980

Patents

Sample Use Guides

In Vivo Use Guide

Six volunteers of mean age 59 years received placebo for week, then fosazepam (60 mg) nightly for 3 weeks, then placebo for 3 weeks

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:49:47 UTC 2023` Edited by `admin` on `Fri Dec 15 15:49:47 UTC 2023`
Record UNII	13AK3H33SG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FOSAZEPAM

Official Name

English

fosazepam [INN]

Common Name

English

FOSAZEPAM [USAN]

Common Name

English

2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-1-((DIMETHYLPHOSPHINYL)METHYL)-1,3-DIHYDRO-5-PHENYL-

Systematic Name

English

HR 930

Code

English

HR-930

Code

English

7-Chloro-1-[(dimethylphosphinyl)methyl]-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1012