MGS-0210

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H28Cl2FNO5
Molecular Weight	476.366
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12C[C@@H](OCC3=CC=C(Cl)C(Cl)=C3)[C@@](N)(C(O)=O)[C@]1([H])[C@@]2(F)C(=O)OCCCCCCC

InChI

InChIKey=SVZJNGHWEHDHLT-OUSKECTQSA-N

InChI=1S/C22H28Cl2FNO5/c1-2-3-4-5-6-9-30-20(29)21(25)14-11-17(22(26,18(14)21)19(27)28)31-12-13-7-8-15(23)16(24)10-13/h7-8,10,14,17-18H,2-6,9,11-12,26H2,1H3,(H,27,28)/t14-,17-,18+,21-,22+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H28Cl2FNO5
Molecular Weight	476.366
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:08:49 GMT 2023` Edited by `admin` on `Sat Dec 16 10:08:49 GMT 2023`
Record UNII	12XH8EKL2A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MGS-0210

Common Name

English

(1R,3R,4R,5R,6R)-4-AMINO-3-((3,4-DICHLOROPHENYL)METHOXY)-6-FLUORO-6-HEPTOXYCARBONYL-BICYCLO(3.1.0)HEXANE-4-CARBOXYLIC ACID

Systematic Name

English

BCI-838

Code

English

(+)-MGS-0210

Common Name

English

BICYCLO(3.1.0)HEXANE-2,6-DICARBOXYLIC ACID, 2-AMINO-3-((3,4-DICHLOROPHENYL)METHOXY)-6-FLUORO-, 6-HEPTYL ESTER, (1R,2R,3R,5R,6R)-

Systematic Name

English

Code System Code Type Description

FDA UNII

12XH8EKL2A

Created by admin on Sat Dec 16 10:08:49 GMT 2023 , Edited by admin on Sat Dec 16 10:08:49 GMT 2023

PRIMARY

PUBCHEM

11641449

Created by admin on Sat Dec 16 10:08:49 GMT 2023 , Edited by admin on Sat Dec 16 10:08:49 GMT 2023

PRIMARY

CAS

820244-38-0

Created by admin on Sat Dec 16 10:08:49 GMT 2023 , Edited by admin on Sat Dec 16 10:08:49 GMT 2023

PRIMARY

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					M8KC1PQ31A

MGS-0039

METABOLITE ACTIVE -> PRODRUG

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					M8KC1PQ31A

MGS-0039

ACTIVE MOIETY

Comments:

Actually, BCI-838 is a "prodrug." It gets converted to its active form, BCI-632, only after being metabolized in the body. BCI-632 blocks proteins in the brain known as Group II metabotropic glutamate receptors. These receptors normally bind with glutamate, a neurotransmitter that is abundant in the brain, to enable memory and other brain functions.