SODIUM ETHASULFATE

US Previously Marketed

First approved in 1955

Details

Stereochemistry	RACEMIC
Molecular Formula	C8H17O4S.Na
Molecular Weight	232.273
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].CCCCC(CC)COS([O-])(=O)=O

InChI

InChIKey=DGSDBJMBHCQYGN-UHFFFAOYSA-M

InChI=1S/C8H18O4S.Na/c1-3-5-6-8(4-2)7-12-13(9,10)11;/h8H,3-7H2,1-2H3,(H,9,10,11);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula	C8H17O4S
Molecular Weight	209.283
Charge	-1
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.transparencymarketresearch.com/sodium-ethasulfate-market.html | https://www.genome.jp/dbget-bin/www_bget?dr:D05858

Sodium ethasulfate is a clear, colorless, viscous, and nonflammable liquid that belongs to the sodium sulfate chemical group. Sodium ethasulfate is usually stable; however, it is incompatible with strong oxidizing agents. Due to its unique solubility and penetrating action, it is widely used in various end-user industries such as textile, chemical production, pharmaceuticals, agrochemicals, metal working, and food processing. Sodium ethasulfate is used as wetting agent in the textile industry. The product is used along with calcium hypochlorite as a bleaching agent. The product is used as mercerizing agent for cotton processing in the chemical industry. Sodium ethasulfate is employed as intermediate in anoinic surfactants that are used for dishwashing detergents. It is also used as surfactant in lye washing and peeling process. In the pharmaceutical industry, it is used to enhance the bactericidal properties of generic antiseptics that are more acidic. It is also employed as surfactant in penicillin production for breaking undesired reaction conditions.

Approval Year

Sourcing

Vendor/Aggregator	ID	URL
ABI Chem	AC1L1LHE
AHH Chemical co.,ltd	MR-1018065	http://www.ahhchemical.com/product/MR-1018065.html
AK Scientific	O101
AK Scientific	P671
AK Scientific, Inc. (AKSCI)	O101	http://www.aksci.com/item_detail.php?cat=O101
Alfa Chemistry	56008-29-8	https://www.alfa-chemistry.com/cas_56008-29-8.htm
Alfa Chemistry	72214-01-8	https://www.alfa-chemistry.com/cas_72214-01-8.htm
Ambeed	A174589
Ambinter	Amb10602107	http://www.ambinter.com/reference/10602107
BLD Pharm	BD00753710	http://www.bldpharm.com/products/72214-01-8.html
BOC Sciences	126-92-1
Bide Pharmatech	BD248486
Chem-Impex International	1577
ChemMol	99140593	http://www.chemmol.com/chemmol/99140593.html
Chemieliva Pharmaceutical Co., Ltd	PBCM1396343
Compound Cloud	23662383
Compound Cloud	31364
Debye Scientific	DB-030357
Enamine	BBV-40197233
Fluorochem	323932
Hairui	HR123128
Lab Network	LN02062571
MolPort	MolPort-003-938-697
MolPort	MolPort-027-947-949
Molcore	CS17120
MuseChem	M067905
NCI Plated 2007	4744
Nanjing Pope Bio-tech	NSTH-D23425
Norris Pharm	NSTH-D23425
Norris Pharm	NSZB-A110920
Sigma Aldrich	71220
Sigma Aldrich	71220\|ALDRICH
Sigma Aldrich	8
Sigma Aldrich	8\|SIGMA
Smolecule	S593545	https://www.smolecule.com/products/s593545
THE BioTek	bt-426154	https://www.thebiotek.com/product/others/bt-426154
Tetrahedron	TS53330
Toronto Research Chemicals	S699405
Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd.	SPI-2125GA
ZINC	ZINC000001680379	http://zinc15.docking.org/substances/ZINC000001680379
ZINC	ZINC000002015520	http://zinc15.docking.org/substances/ZINC000002015520
eMolecules	44842207
eMolecules	44848300
eMolecules	529514
eNovation Chemicals	D769627

PubMed

Title	Date	PubMed
Metabolism of 2-ethylhexyl sulfate by the rat and rabbit.	1966 May	5961556
Experimental toxicity of sodium 2-ethylhexyl sulfate.	1970 Jul	5460439
Comparative chronic toxicities and carcinogenic potentials of 2-ethylhexyl-containing compounds in rats and mice.	1985 Nov	4053278
Carcinogenic potential of phthalic acid esters and related compounds: structure-activity relationships.	1986 Mar	3709453

Patents

Sample Use Guides

In Vivo Use Guide

Sodium ethasulfate (2-ethylhexyl sulfate) (10,000-40,000 ppm) was administered to groups of rats (10,000-20,000 ppm) and mice (5,000-20,000 ppm) for 2 years.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:39:26 UTC 2023` Edited by `admin` on `Fri Dec 15 15:39:26 UTC 2023`
Record UNII	12838560LI
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SODIUM ETHASULFATE

Official Name

English

HEXANOL, 2-ETHYL-, HYDROGEN SULFATE, SODIUM SALT

Common Name

English

SODIUM ETHYLHEXYL SULFATE [INCI]

Common Name

English

SULFURIC ACID, MONO(2-ETHYLHEXYL) ESTER, SODIUM SALT

Common Name

English

SODIUM ETHASULPHATE

Common Name

English

sodium etasulfate [INN]

Common Name

English

SODIUM ETHYLHEXYL SULFATE

Official Name

English

NSC-4744

Code

English

SODIUM ETHASULFATE [USAN]

Common Name

English

(±)-SODIUM ETHASULFATE

Common Name

English

SODIUM 2-ETHYLHEXYL SULFATE

Systematic Name

English

RHODAPON OLS

Brand Name

English

Sodium etasulfate [WHO-DD]

Common Name

English

SODIUM ETHASULFATE, (±)-

Common Name

English

SODIUM ETHASULFATE [HSDB]

Common Name

English

SODIUM ETASULFATE

Official Name

English

Mono(2-ethylhexyl) sulfate sodium salt

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 176.170