NORPIPANONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H29NO
Molecular Weight	335.4825
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NORPIPANONE

Structure Search

SMILES

CCC(=O)C(CCN1CCCCC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=WCDSHELZWCOTMI-UHFFFAOYSA-N

InChI=1S/C23H29NO/c1-2-22(25)23(20-12-6-3-7-13-20,21-14-8-4-9-15-21)16-19-24-17-10-5-11-18-24/h3-4,6-9,12-15H,2,5,10-11,16-19H2,1H3

HIDE SMILES / InChI

Molecular Formula	C23H29NO
Molecular Weight	335.4825
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14051072 | https://www.drugfuture.com/chemdata/norpipanone.html

Norpipanone (Orfenso; Hexalgon) is an opioid analgesic. It is a controlled substance (opiate).

Approval Year

PubMed

PubMed

Title	Date	PubMed
Lower limb amputation and small bowel infarction following parentaral diconal abuse.	1985-03	2858213
Hazards of diconal.	1978-05-06	25116
Misuse of a morphine alternative (Diconal).	1972-08-19	5054485
SOME TRIALS WITH 'ORFENSO', A NEW ANALGESIC.	1963-08-10	14051072

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:18:25 GMT 2025` Edited by `admin` on `Mon Mar 31 18:18:25 GMT 2025`
Record UNII	127X8DJ74M
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

HEXALGON

Preferred Name

English

NORPIPANONE

Official Name

English

IDS-NN-009

Code

English

HOECHST-10495

Code

English

HOECHST 10495

Code

English

ORFENSO-

Common Name

English

norpipanone [INN]

Common Name

English

NORPIPANONE [MI]

Common Name

English

4,4-DIPHENYL-6-(1-PIPERIDYL)-3-HEXANONE

Systematic Name

English

Classification Tree Code System Code

DEA NO.

9636

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

NCI_THESAURUS

C241

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

Code System Code Type Description

FDA UNII

127X8DJ74M

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

PRIMARY

NCI_THESAURUS

C75070

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

PRIMARY

INN

1702

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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CAS

561-48-8

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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SMS_ID

100000083621

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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MERCK INDEX

m852

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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Merck Index

ChEMBL

CHEMBL2105188

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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EPA CompTox

DTXSID60204643

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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EVMPD

SUB09378MIG

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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ECHA (EC/EINECS)

209-220-3

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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WIKIPEDIA

NORPIPANONE

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

PRIMARY

Norpipanone (INN, BAN; Hexalgon) is an opioid analgesic related to methadone which was developed in Germany and distributed in Hungary, Argentina, and other countries.[

PUBCHEM

22391

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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DRUG CENTRAL

3798

Created by admin on Mon Mar 31 18:18:25 GMT 2025 , Edited by admin on Mon Mar 31 18:18:25 GMT 2025

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SALT/SOLVATE -> PARENT

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount:


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NORPIPANONE HYDROBROMIDE

SALT/SOLVATE -> PARENT

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount:

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ACTIVE MOIETY