Enitociclib

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H18F2N4O2S
Molecular Weight	404.434
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(C=CC(F)=C1)C2=CC(NC3=NC=CC(C[S@@](C)(=N)=O)=C3)=NC=C2F

InChI

InChIKey=YZCUMZWULWOUMD-NDEPHWFRSA-N

InChI=1S/C19H18F2N4O2S/c1-27-17-8-13(20)3-4-14(17)15-9-19(24-10-16(15)21)25-18-7-12(5-6-23-18)11-28(2,22)26/h3-10,22H,11H2,1-2H3,(H,23,24,25)/t28-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C19H18F2N4O2S
Molecular Weight	404.434
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Cyclin-dependent kinase 9 24 Target ID: CHEMBL3116 Sources: http://cancerres.aacrjournals.org/content/77/13_Supplement/984	Inhibitor 8504		3.0 nM [IC50]

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 16:26:29 GMT 2025` Edited by `admin` on `Wed Apr 02 16:26:29 GMT 2025`
Record UNII	1255AT22ZJ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

2-Pyridinamine, 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[[[S(S)]-S-methylsulfonimidoyl]methyl]-2-pyridinyl]-

Preferred Name

English

Enitociclib

Official Name

English

BAY-1251152

Code

English

VIP-152

Code

English

enitociclib [INN]

Common Name

English

csc(S)-[(2-{[5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl]amino}pyridin-4-yl)methyl](imino)(methyl)-l6-sulfanone

Systematic Name

English

VIP152

Code

English

ENITOCICLIB [USAN]

Common Name

English

Enitociclib [WHO-DD]

Common Name

English

Code System Code Type Description

FDA UNII

1255AT22ZJ