U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 21:15:14 GMT 2025
Edited
by admin
on Mon Mar 31 21:15:14 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4|KAPPA
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
11Z5AIU653
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AB-0024
Preferred Name English
SIMTUZUMAB
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN LYSYL OXIDASE HOMOLOG 2) (HUMAN-MUS MUSCULUS MONOCLONAL GS-6624 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GS-6624 .KAPPA.-CHAIN, DIMER
Common Name English
SIMTUZUMAB [USAN]
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS LOXL2 (LYSYL OXIDASE-LIKE 2)), HUMANIZED MONOCLONAL ANTIBODY ANTIBODY
Common Name English
AB0024
Code English
Simtuzumab [WHO-DD]
Common Name English
GS-6624
Code English
simtuzumab [INN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 458214
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
FDA ORPHAN DRUG 336611
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
FDA ORPHAN DRUG 340511
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
FDA ORPHAN DRUG 339311
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
NCI_THESAURUS C20401
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
Code System Code Type Description
FDA UNII
11Z5AIU653
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
DRUG BANK
DB12152
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
EVMPD
SUB184161
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
SMS_ID
100000170329
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
WIKIPEDIA
SIMTUZUMAB
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
NCI_THESAURUS
C91735
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
ChEMBL
CHEMBL2109667
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
INN
9626
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
USAN
AB-75
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
CAS
1318075-13-6
Created by admin on Mon Mar 31 21:15:14 GMT 2025 , Edited by admin on Mon Mar 31 21:15:14 GMT 2025
PRIMARY
From To
1_22 1_96
1_143 1_199
1_257 1_317
1_363 1_421
2_22 2_96
2_143 2_199
2_257 2_317
2_363 2_421
3_23 3_93
3_139 3_199
4_23 4_93
4_139 4_199
1_130 3_219
2_130 4_219
1_222 2_222
1_225 2_225
Glycosylation Link Type Site
N 1_293
N 2_293
Related Record Type Details
LYSYL OXIDASE HOMOLOG 2
TARGET -> INHIBITOR
Related Record Type Details
SIMTUZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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DISCLAIMER
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