SIMTUZUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 02:51:50 UTC 2023` Edited by `admin` on `Sat Dec 16 02:51:50 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	11Z5AIU653
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SIMTUZUMAB

Official Name

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN LYSYL OXIDASE HOMOLOG 2) (HUMAN-MUS MUSCULUS MONOCLONAL GS-6624 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GS-6624 .KAPPA.-CHAIN, DIMER

Common Name

English

SIMTUZUMAB [USAN]

Common Name

English

AB-0024

Code

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS LOXL2 (LYSYL OXIDASE-LIKE 2)), HUMANIZED MONOCLONAL ANTIBODY ANTIBODY

Common Name

English

AB0024

Code

English

Simtuzumab [WHO-DD]

Common Name

English

GS-6624

Code

English

simtuzumab [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

458214

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

FDA ORPHAN DRUG

336611

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

FDA ORPHAN DRUG

340511

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

FDA ORPHAN DRUG

339311

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

NCI_THESAURUS

C20401

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

Code System Code Type Description

FDA UNII

11Z5AIU653

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

PRIMARY

DRUG BANK

DB12152

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

PRIMARY

EVMPD

SUB184161

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

PRIMARY

WIKIPEDIA

SIMTUZUMAB

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

PRIMARY

NCI_THESAURUS

C91735

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

PRIMARY

ChEMBL

CHEMBL2109667

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

PRIMARY

INN

9626

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

PRIMARY

USAN

AB-75

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

PRIMARY

CAS

1318075-13-6

Created by admin on Sat Dec 16 02:51:50 UTC 2023 , Edited by admin on Sat Dec 16 02:51:50 UTC 2023

PRIMARY

From	To
1_22	1_96
1_143	1_199
1_257	1_317
1_363	1_421
2_22	2_96
2_143	2_199
2_257	2_317
2_363	2_421
3_23	3_93
3_139	3_199
4_23	4_93
4_139	4_199
1_130	3_219
2_130	4_219
1_222	2_222
1_225	2_225

Glycosylation Link Type	Site
N	1_293
N	2_293

Related Record Type Details


					J2Y8550K5Q

LYSYL OXIDASE HOMOLOG 2

TARGET -> INHIBITOR

Related Record Type Details


					11Z5AIU653

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL